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10.1007/s10096-020-03899-4

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32333222!7180649!32333222
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      Eur+J+Clin+Microbiol+Infect+Dis 2020 ; 39 (9): 1629-1635
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The genetic sequence, origin, and diagnosis of SARS-CoV-2 JO: Eur J Clin Microbiol Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32333222 #FOAvip Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a new infectious disease that first emerged in Hubei province, China, in December 2019, which was found to be associated with a large seafood and animal market in Wuhan. Airway epithelial cells from infected patients were used to isolate a novel coronavirus, named the SARS-CoV-2, on January 12, 2020, which is the seventh member of the coronavirus family to infect humans. Phylogenetic analysis of full-length genome sequences obtained from infected patients showed that SARS-CoV-2 is similar to severe acute respiratory syndrome coronavirus (SARS-CoV) and uses the same cell entry receptor, angiotensin-converting enzyme 2 (ACE2), as SARS-CoV. The possible person-to-person disease rapidly spread to many provinces in China as well as other countries. Without a therapeutic vaccine or specific antiviral drugs, early detection and isolation become essential against novel Coronavirus. In this review, we introduced current diagnostic methods and criteria for the SARS-CoV-2 in China and discuss the advantages and limitations of the current diagnostic methods, including chest imaging and laboratory detection.
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The genetic sequence, origin, and diagnosis of SARS-CoV-2 ????Eur J Clin Microbiol Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32333222 #FOAvip
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<ref>{{Cite pmid|32333222}}</ref>

The genetic sequence, origin, and diagnosis of SARS-CoV-2 #MMPMID32333222
Wang H; Li X; Li T; Zhang S; Wang L; Wu X; Liu J
Eur J Clin Microbiol Infect Dis 2020[Sep]; 39 (9): 1629-1635 PMID32333222show ga
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a new infectious disease that first emerged in Hubei province, China, in December 2019, which was found to be associated with a large seafood and animal market in Wuhan. Airway epithelial cells from infected patients were used to isolate a novel coronavirus, named the SARS-CoV-2, on January 12, 2020, which is the seventh member of the coronavirus family to infect humans. Phylogenetic analysis of full-length genome sequences obtained from infected patients showed that SARS-CoV-2 is similar to severe acute respiratory syndrome coronavirus (SARS-CoV) and uses the same cell entry receptor, angiotensin-converting enzyme 2 (ACE2), as SARS-CoV. The possible person-to-person disease rapidly spread to many provinces in China as well as other countries. Without a therapeutic vaccine or specific antiviral drugs, early detection and isolation become essential against novel Coronavirus. In this review, we introduced current diagnostic methods and criteria for the SARS-CoV-2 in China and discuss the advantages and limitations of the current diagnostic methods, including chest imaging and laboratory detection.
|*Clinical Laboratory Techniques[MESH]
|Alanine Transaminase/metabolism[MESH]
|Animals[MESH]
|Antibodies, Viral/blood[MESH]
|Betacoronavirus/*genetics[MESH]
|C-Reactive Protein/metabolism[MESH]
|COVID-19[MESH]
|COVID-19 Testing[MESH]
|COVID-19 Vaccines[MESH]
|China[MESH]
|Chiroptera/virology[MESH]
|Coronavirus Envelope Proteins[MESH]
|Coronavirus Infections/*diagnosis/metabolism/transmission[MESH]
|Coronavirus Nucleocapsid Proteins[MESH]
|Coronavirus RNA-Dependent RNA Polymerase[MESH]
|Coronavirus/genetics[MESH]
|Cytokines/metabolism[MESH]
|Ferritins/metabolism[MESH]
|Fibrin Fibrinogen Degradation Products/metabolism[MESH]
|Genome, Viral/*genetics[MESH]
|Humans[MESH]
|Immunoglobulin G/immunology[MESH]
|L-Lactate Dehydrogenase/metabolism[MESH]
|Leukopenia[MESH]
|Lung/*diagnostic imaging[MESH]
|Lymphopenia[MESH]
|Nucleocapsid Proteins/genetics[MESH]
|Pandemics[MESH]
|Phosphoproteins[MESH]
|Pneumonia, Viral/*diagnosis/metabolism/transmission[MESH]
|Polyproteins[MESH]
|RNA-Dependent RNA Polymerase/genetics[MESH]
|Real-Time Polymerase Chain Reaction[MESH]
|Reverse Transcriptase Polymerase Chain Reaction[MESH]
|SARS-CoV-2[MESH]
|Sensitivity and Specificity[MESH]
|Severe acute respiratory syndrome-related coronavirus/genetics[MESH]
|Spike Glycoprotein, Coronavirus/genetics[MESH]
|Tomography, X-Ray Computed[MESH]
|Viral Envelope Proteins/genetics[MESH]
|Viral Nonstructural Proteins/genetics[MESH]The genetic sequence, origin, and diagnosis of SARS-CoV-2 (epmc).pdf

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