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Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Int+J+Quantum+Chem 2011 ; 111 (14): 3971-3979 Nephropedia Template TP
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A novel way to numerically characterize DNA sequences and its application #MMPMID32327765
Guo Y; Wang YF; Zhang SL
Int J Quantum Chem 2011[Nov]; 111 (14): 3971-3979 PMID32327765show ga
We presented a novel way to numerically characterize DNA sequences based on the graphical representation for the sequences comparison and analysis. Instead of calculating the leading eigenvalues of the matrix for graphical representation, we computed curvature and torsion of curves as the descriptor to numerically characterize DNA sequences. The new method was tested on three data sets: the coding sequences of beta-globin gene, all of their exons, and 24 coronavirus geneomes from NCBI. The similarities/dissimilarities and phylogenetic tree of these species verify the validity of our method. (c) 2010 Wiley Periodicals, Inc. Int J Quantum Chem, 2011.