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10.3390/jcm9041126

http://scihub22266oqcxt.onion/10.3390/jcm9041126
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suck abstract from ncbi


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pmid32326426      J+Clin+Med 2020 ; 9 (4): ä
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  • COVID-19: A Recommendation to Examine the Effect of Mouthrinses with beta-Cyclodextrin Combined with Citrox in Preventing Infection and Progression #MMPMID32326426
  • Carrouel F; Conte MP; Fisher J; Goncalves LS; Dussart C; Llodra JC; Bourgeois D
  • J Clin Med 2020[Apr]; 9 (4): ä PMID32326426show ga
  • Considered to be a major portal of entry for infectious agents, the oral cavity is directly associated with the evolutionary process of SARS-CoV-2 in its inhalation of ambient particles in the air and in expectorations. Some new generations of mouth rinses currently on the market have ingredients that could contribute to lower the SARS-CoV-2 viral load, and thus facilitate the fight against oral transmission. If chlorhexidine, a usual component of mouth rinse, is not efficient to kill SARS-CoV-2, the use of a mouth rinses and/or with local nasal applications that contain beta-cyclodextrins combined with flavonoids agents, such as Citrox, could provide valuable adjunctive treatment to reduce the viral load of saliva and nasopharyngeal microbiota, including potential SARS-CoV-2 carriage. We urge national agencies and authorities to start clinical trials to evaluate the preventive effects of betaCD-Citrox therapeutic oral biofilm rinses in reducing the viral load of the infection and possibly disease progression.
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