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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Immunity 2020 ; 52 (5): 731-733 Nephropedia Template TP
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COVID-19: A New Virus, but a Familiar Receptor and Cytokine Release Syndrome #MMPMID32325025
Hirano T; Murakami M
Immunity 2020[May]; 52 (5): 731-733 PMID32325025show ga
Zhou et al. (Nature) and Hoffmann et al. (Cell) identify ACE2 as a SARS-CoV-2 receptor, and the latter show its entry mechanism depends on cellular serine protease TMPRSS2. These results may explain proinflammatory cytokine release via the associated angiotestin II pathway and a possible therapeutic target via the IL-6-STAT3 axis.