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  • COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine #MMPMID32324331
  • Fontana F; Alfano G; Mori G; Amurri A; Tei L; Ballestri M; Leonelli M; Facchini F; Damiano F; Magistroni R; Cappelli G
  • Am J Transplant 2020[Jul]; 20 (7): 1902-1906 PMID32324331show ga
  • Coronavirus disease 2019 (COVID-19) pneumonia has been poorly reported in solid organ transplanted patients; prognosis is uncertain and best management unclear. We describe the case of a 61-year-old kidney transplant recipient with several comorbidities who was hospitalized and later received a diagnosis of COVID-19 pneumonia; the infection was successfully managed with the use of hydroxychloroquine and a single administration of tocilizumab, after immunosuppression reduction; the patient did not require mechanical ventilation. During the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, transplant clinicians should be readily informed about new cases of COVID-19 pneumonia in solid organ transplant recipients, with focus on therapeutic strategies employed and their outcome.
  • |*Kidney Transplantation[MESH]
  • |Antibodies, Monoclonal, Humanized/*administration & dosage[MESH]
  • |Antiviral Agents/administration & dosage[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Comorbidity[MESH]
  • |Coronavirus Infections/complications/drug therapy/*therapy[MESH]
  • |Humans[MESH]
  • |Hydroxychloroquine/*administration & dosage[MESH]
  • |Immunosuppressive Agents/*administration & dosage[MESH]
  • |Kidney Failure, Chronic/*complications/surgery[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Nephritis, Interstitial/*complications/surgery[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/complications/*therapy[MESH]
  • |Respiration, Artificial[MESH]
  • |Risk Assessment[MESH]
  • |SARS-CoV-2[MESH]
  • |Treatment Outcome[MESH]

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  • suck abstract from ncbi

    1902 7.20 2020