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10.4269/ajtmh.20-0276

http://scihub22266oqcxt.onion/10.4269/ajtmh.20-0276
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32314698!7253107!32314698
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suck abstract from ncbi


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pmid32314698      Am+J+Trop+Med+Hyg 2020 ; 102 (6): 1214-1216
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  • Case Report: Hepatotoxicity Associated with the Use of Hydroxychloroquine in a Patient with COVID-19 #MMPMID32314698
  • Falcao MB; Pamplona de Goes Cavalcanti L; Filgueiras Filho NM; Antunes de Brito CA
  • Am J Trop Med Hyg 2020[Jun]; 102 (6): 1214-1216 PMID32314698show ga
  • Hydroxychloroquine (HCQ) has been used for the treatment of novel coronavirus disease (COVID-19) cases. However, evidence of efficacy remains limited, and adverse events can be associated with its use. Here, we report a case of a patient with severe COVID-19 who, after being administered HCQ, exhibited a 10-fold increase in serum levels of transaminases, followed by a rapid decrease after HCQ was withdrawn. Considering the significantly increased use of HCQ during the COVID-19 pandemic, this case alerts us to the potential for HCQ to be associated with hepatotoxicity and the need to monitor liver function during HCQ therapy.
  • |Adult[MESH]
  • |Alanine Transaminase/blood[MESH]
  • |Aspartate Aminotransferases/blood[MESH]
  • |Azithromycin/therapeutic use[MESH]
  • |Betacoronavirus/drug effects/isolation & purification/*pathogenicity[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/diagnostic imaging/immunology/pathology/*therapy[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Hydroxychloroquine/administration & dosage/*adverse effects[MESH]
  • |Liver/diagnostic imaging/*drug effects/pathology/virology[MESH]
  • |Lung/diagnostic imaging/drug effects/pathology/virology[MESH]
  • |Pandemics[MESH]
  • |Piperacillin, Tazobactam Drug Combination/therapeutic use[MESH]
  • |Pneumonia, Viral/diagnostic imaging/immunology/pathology/*therapy[MESH]
  • |Respiration, Artificial[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]


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