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10.1152/ajpendo.00150.2020 http://scihub22266oqcxt.onion/10.1152/ajpendo.00150.2020 32310688!7215091!32310688     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Physiol+Endocrinol+Metab 2020 ; 318 (5): E830-E833 Nephropedia Template TP {{tp|p=32310688|t=2020. Biological plausibility for interactions between dietary fat, resveratrol, ACE2, and SARS-CoV illness severity |pdf=|usr=}}{{32310688}} gab.com Text Biological plausibility for interactions between dietary fat, resveratrol, ACE2, and SARS-CoV illness severity JO: Am J Physiol Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=32310688 #FOAvip The angiotensin converting enzyme-2 (ACE2) cellular receptor is responsible for the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), thus impacting the entrance and clearance of the virus. Studies demonstrate that upregulation of ACE2 has a protective effect on SARS-CoV-2 illness severity. Moreover, animal studies demonstrate that dietary intake can modulate ACE2 gene expression and function. A high intake of resveratrol may have a protective role, upregulating ACE2, whereas a high intake of dietary fat may have a detrimental role, downregulating ACE2. As such, we postulate on the biological plausibility of interactions between dietary fat and/or resveratrol and ACE2 gene variations in the modulation of SARS-CoV-2 illness severity. We call to action the research community to test this plausible interaction in a sample of human subjects. Twit Text FOAVip Biological plausibility for interactions between dietary fat, resveratrol, ACE2, and SARS-CoV illness severity ????Am J Physiol Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=32310688 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32310688 #FOAvip English Wikipedia <ref>{{Cite pmid|32310688}}</ref> Biological plausibility for interactions between dietary fat, resveratrol, ACE2, and SARS-CoV illness severity #MMPMID32310688 Horne JR; Vohl MC Am J Physiol Endocrinol Metab 2020[May]; 318 (5): E830-E833 PMID32310688show ga The angiotensin converting enzyme-2 (ACE2) cellular receptor is responsible for the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), thus impacting the entrance and clearance of the virus. Studies demonstrate that upregulation of ACE2 has a protective effect on SARS-CoV-2 illness severity. Moreover, animal studies demonstrate that dietary intake can modulate ACE2 gene expression and function. A high intake of resveratrol may have a protective role, upregulating ACE2, whereas a high intake of dietary fat may have a detrimental role, downregulating ACE2. As such, we postulate on the biological plausibility of interactions between dietary fat and/or resveratrol and ACE2 gene variations in the modulation of SARS-CoV-2 illness severity. We call to action the research community to test this plausible interaction in a sample of human subjects. |*Diet[MESH] |Angiotensin-Converting Enzyme 2[MESH] |Animals[MESH] |Betacoronavirus/metabolism[MESH] |COVID-19[MESH] |Coronavirus Infections/*physiopathology[MESH] |Dietary Fats/*pharmacology[MESH] |Female[MESH] |Gene Expression Regulation/*drug effects[MESH] |Humans[MESH] |Male[MESH] |Mice[MESH] |Pandemics[MESH] |Peptidyl-Dipeptidase A/*genetics/metabolism[MESH] |Pneumonia, Viral/*physiopathology[MESH] |Rats[MESH] |Resveratrol/*pharmacology[MESH] |SARS-CoV-2[MESH]Biological plausibility for interactions between dietary fat, resverat(epmc).pdf DeepDyve Pubget Overpricing