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10.1016/j.jcv.2020.104356

http://scihub22266oqcxt.onion/10.1016/j.jcv.2020.104356
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32302955!7194834!32302955
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suck abstract from ncbi


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pmid32302955      J+Clin+Virol 2020 ; 127 (ä): 104356
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  • Clinical characteristics and risk assessment of newborns born to mothers with COVID-19 #MMPMID32302955
  • Yang P; Wang X; Liu P; Wei C; He B; Zheng J; Zhao D
  • J Clin Virol 2020[Jun]; 127 (ä): 104356 PMID32302955show ga
  • BACKGROUND: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is causing an outbreak of pneumonia in Wuhan, Hubei Province, China, and other international areas. OBJECTIVE: Here, we report the clinical characteristics of the newborns delivered by SARS-CoV-2 infected pregnant women. METHODS: We prospectively collected and analyzed the clinical features, laboratory data and outcomes of 7 newborns delivered by SARS-CoV-2 infected pregnant women in Zhongnan Hospital of Wuhan University during January 20 to January 29, 2020. RESULTS: 4 of the 7 newborns were late preterm with gestational age between 36 weeks and 37 weeks, and the other 3 were full-term infants. The average birth weight was 2096 +/- 660 g. All newborns were born without asphyxia. 2 premature infants performed mild grunting after birth, but relieved rapidly with non-invasive continuous positive airway pressure (nCPAP) ventilation. 3 cases had chest X-ray, 1 was normal and 2 who were supported by nCPAP presented mild neonatal respiratory distress syndrome (NRDS). Samples of pharyngeal swab in 6 cases, amniotic fluid and umbilical cord blood in 4 cases were tested by qRT-PCR, and there was no positive result of SARS-CoV-2 nucleic acid in all cases. CONCLUSIONS: The current data show that the infection of SARS-CoV-2 in late pregnant women does not cause adverse outcomes in their newborns, however, it is necessary to separate newborns from mothers immediately to avoid the potential threats.
  • |*Infectious Disease Transmission, Vertical[MESH]
  • |Amniotic Fluid/virology[MESH]
  • |Betacoronavirus[MESH]
  • |Birth Weight[MESH]
  • |COVID-19[MESH]
  • |China/epidemiology[MESH]
  • |Continuous Positive Airway Pressure[MESH]
  • |Coronavirus Infections/*diagnosis/epidemiology[MESH]
  • |Female[MESH]
  • |Fetal Blood/virology[MESH]
  • |Gestational Age[MESH]
  • |Humans[MESH]
  • |Infant Health[MESH]
  • |Infant, Newborn[MESH]
  • |Infant, Premature[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnosis/epidemiology[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Complications, Infectious/*virology[MESH]
  • |Prospective Studies[MESH]
  • |Risk Assessment[MESH]
  • |SARS-CoV-2[MESH]
  • |Thorax/diagnostic imaging/virology[MESH]


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