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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Int+J+Antimicrob+Agents 2020 ; 56 (2): 105974 Nephropedia Template TP
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Successful treatment with plasma exchange followed by intravenous immunoglobulin in a critically ill patient with COVID-19 #MMPMID32298745
Shi H; Zhou C; He P; Huang S; Duan Y; Wang X; Lin K; Zhou C; Zhang X; Zha Y
Int J Antimicrob Agents 2020[Aug]; 56 (2): 105974 PMID32298745show ga
Here we report a case of a laboratory-confirmed 2019 novel coronavirus (2019-nCoV)-infected patient with COVID-19 (coronavirus disease 2019) who developed respiratory failure and shock accompanied by persistent diarrhoea despite conventional therapeutic interventions. The patient avoided mechanical ventilation and showed an immediate clinical and radiological improvement following treatment with intensive plasma exchange (PE) followed by intravenous immunoglobulin (IVIG). Successful therapeutic strategies in this case suggest that timely initiation of PE treatment followed by IVIG in critically ill patients with COVID-19 may prevent the disease from worsening and help to reduce the requirement for mechanical ventilation and intensive supportive care. Moreover, it may improve poor clinical outcomes of these patients.