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10.1016/j.jtho.2020.04.003

http://scihub22266oqcxt.onion/10.1016/j.jtho.2020.04.003
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suck abstract from ncbi


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pmid32289516      J+Thorac+Oncol 2020 ; 15 (6): 1065-1072
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  • Coronavirus Disease 2019 in the Perioperative Period of Lung Resection: A Brief Report From a Single Thoracic Surgery Department in Wuhan, People s Republic of China #MMPMID32289516
  • Cai Y; Hao Z; Gao Y; Ping W; Wang Q; Peng S; Zhao B; Sun W; Zhu M; Li K; Han Y; Kuang D; Chu Q; Fu X; Zhang N
  • J Thorac Oncol 2020[Jun]; 15 (6): 1065-1072 PMID32289516show ga
  • Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that was first reported in Wuhan, People's Republic of China, and has subsequently spread worldwide. Clinical information on patients who contracted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the perioperative period is limited. Here, we report seven cases with confirmed SARS-CoV-2 infection in the perioperative period of lung resection. Retrospective analysis suggested that one patient had been infected with the SARS-CoV-2 infection before the surgery and the other six patients contracted the infection after the lung resection. Fever, lymphopenia, and ground-glass opacities revealed on computed tomography are the most common clinical manifestations of the patients who contracted COVID-19 after the lung resection. Pathologic studies of the specimens of these seven patients were performed. Pathologic examination of patient 1, who was infected with the SARS-CoV-2 infection before the surgery, revealed that apart from the tumor, there was a wide range of interstitial inflammation with plasma cell and macrophage infiltration. High density of macrophages and foam cells in the alveolar cavities, but no obvious proliferation of pneumocyte, was found. Three of seven patients died from COVID-19 pneumonia, suggesting lung resection surgery might be a risk factor for death in patients with COVID-19 in the perioperative period.
  • |*Betacoronavirus[MESH]
  • |*Pneumonectomy[MESH]
  • |*Surgicenters[MESH]
  • |*Thoracic Surgery[MESH]
  • |Aged[MESH]
  • |Biopsy[MESH]
  • |COVID-19[MESH]
  • |China/epidemiology[MESH]
  • |Coronavirus Infections/*complications/diagnosis/epidemiology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Lung Neoplasms/*complications/epidemiology/surgery[MESH]
  • |Lung/*diagnostic imaging/surgery[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Perioperative Period[MESH]
  • |Pneumonia, Viral/*complications/diagnosis/epidemiology[MESH]
  • |SARS-CoV-2[MESH]


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