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10.1016/j.clim.2020.108420 http://scihub22266oqcxt.onion/10.1016/j.clim.2020.108420 32283324!7151358!32283324     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Immunol 2020 ; 214 (ä): 108420 Nephropedia Template TP {{tp|p=32283324|t=2020. COVID-19 - Considerations for the paediatric rheumatologist |pdf=|usr=}}{{32283324}} gab.com Text COVID-19 - Considerations for the paediatric rheumatologist JO: Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32283324 #FOAvip The novel coronavirus SARS-CoV2 is a threat to the health and well-being of millions of lifes across the globe. A significant proportion of adult patients require hospitalisation and may develop severe life-threatening complications. Children, on the other hand, can carry and transmit the virus, but usually do not develop severe disease. Mortality in the paediatric age-group is relatively low. Differences in virus containment and clearance, as well as reduced inflammation-related tissue and organ damage may be caused by age-specific environmental and host factors. Since severe complications in adults are frequently caused by uncontrolled immune responses and a resulting "cytokine storm" that may be controlled by targeted blockade of cytokines, previously established treatment with immunosuppressive treatments may indeed protect children from complications. Twit Text FOAVip COVID-19 - Considerations for the paediatric rheumatologist ????Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32283324 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32283324 #FOAvip English Wikipedia <ref>{{Cite pmid|32283324}}</ref> COVID-19 - Considerations for the paediatric rheumatologist #MMPMID32283324 Hedrich CM Clin Immunol 2020[May]; 214 (ä): 108420 PMID32283324show ga The novel coronavirus SARS-CoV2 is a threat to the health and well-being of millions of lifes across the globe. A significant proportion of adult patients require hospitalisation and may develop severe life-threatening complications. Children, on the other hand, can carry and transmit the virus, but usually do not develop severe disease. Mortality in the paediatric age-group is relatively low. Differences in virus containment and clearance, as well as reduced inflammation-related tissue and organ damage may be caused by age-specific environmental and host factors. Since severe complications in adults are frequently caused by uncontrolled immune responses and a resulting "cytokine storm" that may be controlled by targeted blockade of cytokines, previously established treatment with immunosuppressive treatments may indeed protect children from complications. |*Pediatrics[MESH] |*Rheumatology[MESH] |Age Factors[MESH] |Betacoronavirus[MESH] |COVID-19[MESH] |Child[MESH] |Coinfection/virology[MESH] |Comorbidity[MESH] |Coronavirus Infections/*epidemiology/pathology[MESH] |Cytokines/immunology[MESH] |Humans[MESH] |Immune Evasion[MESH] |Immunosuppressive Agents/administration & dosage[MESH] |Pandemics[MESH] |Pneumonia, Viral/*epidemiology/pathology[MESH]COVID-19 - Considerations for the paediatric rheumatologist (epmc).pdf DeepDyve Pubget Overpricing