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10.1016/j.accpm.2020.04.001 http://scihub22266oqcxt.onion/10.1016/j.accpm.2020.04.001 32278670!7144603!32278670     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\32278670.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Anaesth+Crit+Care+Pain+Med 2020 ; 39 (5): 553-561 Nephropedia Template TP {{tp|p=32278670|t=2020. SARS-CoV-2 in Spanish Intensive Care Units: Early experience with 15-day survival in Vitoria |pdf=|usr=}}{{32278670}} gab.com Text SARS-CoV-2 in Spanish Intensive Care Units: Early experience with 15-day survival in Vitoria JO: Anaesth Crit Care Pain Med http://www.kidney.de/pget.php?&tw=1&pmid=32278670 #FOAvip PURPOSE: Community transmission of SARS-CoV-2 was detected in Spain in February 2020, with 216% intensive care unit (ICU) capacity expanded in Vitoria by March 18(th), 2020. METHODS: We identified patients from the two public hospitals in Vitoria who were admitted to ICU with confirmed infection by SARS-CoV-2. Data reported here were available in April 6th, 2020. Mortality was assessed in those who completed 15-days of ICU stay. RESULTS: We identified 48 patients (27 males) with confirmed SARS-CoV-2. Median [interquartile range (IQR)] age of patients was 63 [51-75] years. Symptoms began a median of 7 [5-12] days before ICU admission. The most common comorbidities identified were obesity (48%), arterial hypertension (44%) and chronic lung disease (37%). All patients were admitted by hypoxemic respiratory failure and none received non-invasive mechanical ventilation. Forty-five (94%) underwent intubation, 3 (6%) high flow nasal therapy (HFNT), 1 (2%) extracorporeal membrane oxygenation (ECMO) and 22 (46%) required prone position. After 15 days, 14/45 (31%) intubated patients died (13% within one week), 10/45 (22%) were extubated, and 21/45 (47%) underwent mechanical ventilation. Six patients had documented super-infection. Procalcitonin plasma above 0.5mug/L was associated with 16% vs. 19% (p=0.78) risk of death after 7 days. CONCLUSION: This early experience with SARS-CoV-2 in Spain suggests that a strategy of right oxygenation avoiding non-invasive mechanical ventilation was life-saving. Seven-day mortality in SARS-CoV-2 requiring intubation was lower than 15%, with 80% of patients still requiring mechanical ventilation. After 15 days of ICU admission, half of patients remained intubated, whereas one third died. Twit Text FOAVip SARS-CoV-2 in Spanish Intensive Care Units: Early experience with 15-day survival in Vitoria ????Anaesth Crit Care Pain Med http://www.kidney.de/pget.php?&tw=1&pmid=32278670 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32278670 #FOAvip English Wikipedia <ref>{{Cite pmid|32278670}}</ref> SARS-CoV-2 in Spanish Intensive Care Units: Early experience with 15-day survival in Vitoria #MMPMID32278670 Barrasa H; Rello J; Tejada S; Martin A; Balziskueta G; Vinuesa C; Fernandez-Miret B; Villagra A; Vallejo A; San Sebastian A; Cabanes S; Iribarren S; Fonseca F; Maynar J Anaesth Crit Care Pain Med 2020[Oct]; 39 (5): 553-561 PMID32278670show ga PURPOSE: Community transmission of SARS-CoV-2 was detected in Spain in February 2020, with 216% intensive care unit (ICU) capacity expanded in Vitoria by March 18(th), 2020. METHODS: We identified patients from the two public hospitals in Vitoria who were admitted to ICU with confirmed infection by SARS-CoV-2. Data reported here were available in April 6th, 2020. Mortality was assessed in those who completed 15-days of ICU stay. RESULTS: We identified 48 patients (27 males) with confirmed SARS-CoV-2. Median [interquartile range (IQR)] age of patients was 63 [51-75] years. Symptoms began a median of 7 [5-12] days before ICU admission. The most common comorbidities identified were obesity (48%), arterial hypertension (44%) and chronic lung disease (37%). All patients were admitted by hypoxemic respiratory failure and none received non-invasive mechanical ventilation. Forty-five (94%) underwent intubation, 3 (6%) high flow nasal therapy (HFNT), 1 (2%) extracorporeal membrane oxygenation (ECMO) and 22 (46%) required prone position. After 15 days, 14/45 (31%) intubated patients died (13% within one week), 10/45 (22%) were extubated, and 21/45 (47%) underwent mechanical ventilation. Six patients had documented super-infection. Procalcitonin plasma above 0.5mug/L was associated with 16% vs. 19% (p=0.78) risk of death after 7 days. CONCLUSION: This early experience with SARS-CoV-2 in Spain suggests that a strategy of right oxygenation avoiding non-invasive mechanical ventilation was life-saving. Seven-day mortality in SARS-CoV-2 requiring intubation was lower than 15%, with 80% of patients still requiring mechanical ventilation. After 15 days of ICU admission, half of patients remained intubated, whereas one third died. |*Betacoronavirus[MESH] |*Pandemics[MESH] |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Antiviral Agents/therapeutic use[MESH] |COVID-19[MESH] |COVID-19 Drug Treatment[MESH] |Combined Modality Therapy[MESH] |Comorbidity[MESH] |Coronavirus Infections/blood/complications/drug therapy/*mortality/therapy[MESH] |Disease Outbreaks[MESH] |Female[MESH] |Hospital Mortality[MESH] |Hospitals, Public/*statistics & numerical data[MESH] |Humans[MESH] |Influenza, Human/epidemiology[MESH] |Intensive Care Units/*statistics & numerical data[MESH] |Kaplan-Meier Estimate[MESH] |Length of Stay[MESH] |Male[MESH] |Middle Aged[MESH] |Oxygen Inhalation Therapy[MESH] |Pneumonia, Viral/blood/complications/*mortality/therapy[MESH] |Procalcitonin/blood[MESH] |Respiration, Artificial[MESH] |Respiratory Distress Syndrome/etiology/mortality/therapy[MESH] |SARS-CoV-2[MESH]SARS-CoV-2 in Spanish Intensive Care Units: Early experience with 15-d(epmc).pdf DeepDyve Pubget Overpricing