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  • Novel coronavirus (SARS-CoV-2) infection in a renal transplant recipient: Case report #MMPMID32277555
  • Ning L; Liu L; Li W; Liu H; Wang J; Yao Z; Zhang S; Zhao D; Nashan B; Shen A; Liu L; Li L
  • Am J Transplant 2020[Jul]; 20 (7): 1864-1868 PMID32277555show ga
  • An ongoing outbreak of pneumonia associated with the severe acute respiratory coronavirus 2 (SARS-CoV-2) started in Wuhan, China, with cases now confirmed in multiple countries. The clinical course of patients remains to be fully characterized, clinical presentation ranges from asymptomatic infection to acute respiratory distress syndrome and acute renal failure, and no pharmacological therapies of proven efficacy yet exist. We report a case of SARS-CoV-2 infection in a renal transplant recipient with excellent outcome. This case states the importance of close monitoring of the concentration of cyclosporine in patients treated with lopinavir/ritonavir; the routine treatment of corticosteroid can be continued. This is a rare report of SARS-CoV-2 infection in a renal transplant recipient. Further data are needed to achieve better understanding of the impact of immunosuppressive therapy on the clinical presentation, severity, and outcome of SARS-CoV-2 infections in solid organ transplant recipients.
  • |*Kidney Transplantation[MESH]
  • |*Transplant Recipients[MESH]
  • |Adrenal Cortex Hormones/administration & dosage[MESH]
  • |Adult[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |China/epidemiology[MESH]
  • |Coronavirus Infections/*complications/diagnosis/therapy[MESH]
  • |Cyclosporine/administration & dosage/*blood[MESH]
  • |Disease Outbreaks[MESH]
  • |Drug Combinations[MESH]
  • |Humans[MESH]
  • |Immunosuppression/*adverse effects[MESH]
  • |Immunosuppressive Agents/administration & dosage[MESH]
  • |Kidney Failure, Chronic/complications/*surgery[MESH]
  • |Living Donors[MESH]
  • |Lopinavir/administration & dosage[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications/diagnosis/therapy[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |Ritonavir/administration & dosage[MESH]
  • |SARS-CoV-2[MESH]
  • |Tomography, X-Ray Computed[MESH]
  • |Treatment Outcome[MESH]

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  • suck abstract from ncbi

    1864 7.20 2020