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Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 PLoS+One 2020 ; 15 (4): e0231164 Nephropedia Template TP
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Ozone efficacy for the control of airborne viruses: Bacteriophage and norovirus models #MMPMID32275685
Dubuis ME; Dumont-Leblond N; Laliberte C; Veillette M; Turgeon N; Jean J; Duchaine C
PLoS One 2020[]; 15 (4): e0231164 PMID32275685show ga
This study was designed to test the efficacy of an air treatment using ozone and relative humidity (RH) for the inactivation of airborne viruses. Four phages (phiX174, PR772, MS2 and phi6) and one eukaryotic virus (murine norovirus MNV-1) were exposed to low ozone concentrations (1.23 ppm for phages and 0.23 ppm for MNV-1) and various levels of RH for 10 to 70 minutes. The inactivation of these viruses was then assessed to determine which of the tested conditions provided the greatest reduction in virus infectivity. An inactivation of at least two orders of magnitude for phiX174, MS2 and MNV-1 was achieved with an ozone exposure of 40 minutes at 85% RH. For PR772 and phi6, exposure to the reference condition at 20% RH for 10 minutes yielded the same results. These findings suggest that ozone used at a low concentration is a powerful disinfectant for airborne viruses when combined with a high RH. Air treatment could therefore be implemented inside hospital rooms ventilated naturally.
|*Air Microbiology[MESH]
|Animals[MESH]
|Bacteriophage phi X 174/drug effects/isolation & purification/pathogenicity[MESH]