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Myocardial localization of coronavirus in COVID-19 cardiogenic shock #MMPMID32275347
Tavazzi G; Pellegrini C; Maurelli M; Belliato M; Sciutti F; Bottazzi A; Sepe PA; Resasco T; Camporotondo R; Bruno R; Baldanti F; Paolucci S; Pelenghi S; Iotti GA; Mojoli F; Arbustini E
Eur J Heart Fail 2020[May]; 22 (5): 911-915 PMID32275347show ga
We describe the first case of acute cardiac injury directly linked to myocardial localization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a 69-year-old patient with flu-like symptoms rapidly degenerating into respiratory distress, hypotension, and cardiogenic shock. The patient was successfully treated with venous-arterial extracorporeal membrane oxygenation (ECMO) and mechanical ventilation. Cardiac function fully recovered in 5 days and ECMO was removed. Endomyocardial biopsy demonstrated low-grade myocardial inflammation and viral particles in the myocardium suggesting either a viraemic phase or, alternatively, infected macrophage migration from the lung.