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COVID-19: immunopathology and its implications for therapy #MMPMID32273594
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Nat Rev Immunol 2020[May]; 20 (5): 269-270 PMID32273594show ga
Severe coronavirus disease 2019 (COVID-19) is characterized by pneumonia, lymphopenia, exhausted lymphocytes and a cytokine storm. Significant antibody production is observed; however, whether this is protective or pathogenic remains to be determined. Defining the immunopathological changes in patients with COVID-19 provides potential targets for drug discovery and is important for clinical management.