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10.1002/jmv.25839

http://scihub22266oqcxt.onion/10.1002/jmv.25839
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suck abstract from ncbi


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pmid32270515      J+Med+Virol 2020 ; 92 (7): 915-918
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  • Does recombinant human erythropoietin administration in critically ill COVID-19 patients have miraculous therapeutic effects? #MMPMID32270515
  • Hadadi A; Mortezazadeh M; Kolahdouzan K; Alavian G
  • J Med Virol 2020[Jul]; 92 (7): 915-918 PMID32270515show ga
  • An 80-year-old man with multiple comorbidities presented to the emergency department with tachypnea, tachycardia, fever, and critically low O(2) saturation and definitive chest computerized tomography scan findings in favor of COVID-19 and positive PCR results in 48 hours. He received antiviral treatment plus recombinant human erythropoietin (rhEPO) due to his severe anemia. After 7 days of treatment, he was discharged with miraculous improvement in his symptoms and hemoglobin level. We concluded that rhEPO could attenuate respiratory distress syndrome and confront the severe acute respiratory syndrome coronavirus 2 virus through multiple mechanisms including cytokine modulation, antiapoptotic effects, leukocyte release from bone marrow, and iron redistribution away from the intracellular virus.
  • |Aged, 80 and over[MESH]
  • |Anemia/complications/diagnosis/*drug therapy/virology[MESH]
  • |Antiviral Agents/therapeutic use[MESH]
  • |Betacoronavirus/drug effects/genetics/pathogenicity[MESH]
  • |Biomarkers/blood[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques/methods[MESH]
  • |Convalescence[MESH]
  • |Coronavirus Infections/complications/diagnosis/*drug therapy/virology[MESH]
  • |Critical Illness[MESH]
  • |Erythropoietin/*therapeutic use[MESH]
  • |Fever/complications/diagnosis/*drug therapy/virology[MESH]
  • |Humans[MESH]
  • |Iran[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/complications/diagnosis/*drug therapy/virology[MESH]
  • |RNA, Viral/blood/genetics[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]
  • |Tachycardia/complications/diagnosis/*drug therapy/virology[MESH]
  • |Tachypnea/complications/diagnosis/*drug therapy/virology[MESH]
  • |Tomography, X-Ray Computed[MESH]


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