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10.1183/13993003.00688-2020

http://scihub22266oqcxt.onion/10.1183/13993003.00688-2020
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32269089!7144263!32269089
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suck abstract from ncbi


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pmid32269089      Eur+Respir+J 2020 ; 55 (5): ä
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  • ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 #MMPMID32269089
  • Leung JM; Yang CX; Tam A; Shaipanich T; Hackett TL; Singhera GK; Dorscheid DR; Sin DD
  • Eur Respir J 2020[May]; 55 (5): ä PMID32269089show ga
  • Smokers and those with COPD have increased airway expression of ACE-2, which is the entry receptor for the COVID-19 virus. This may explain the increased risk of severe COVID-19 in these subpopulations and highlight the importance of smoking cessation. https://bit.ly/3bC29es
  • |*Up-Regulation[MESH]
  • |Acute Lung Injury/complications/metabolism[MESH]
  • |Adult[MESH]
  • |Angiotensin-Converting Enzyme 2[MESH]
  • |COVID-19[MESH]
  • |Case-Control Studies[MESH]
  • |Cohort Studies[MESH]
  • |Coronavirus Infections/complications/diagnosis/*metabolism/prevention & control[MESH]
  • |Epithelium/*metabolism[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Lung/metabolism[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics/prevention & control[MESH]
  • |Peptidyl-Dipeptidase A/*genetics/*metabolism[MESH]
  • |Pneumonia, Viral/complications/diagnosis/*metabolism/prevention & control[MESH]
  • |Pulmonary Disease, Chronic Obstructive/complications/genetics/*metabolism[MESH]
  • |RNA-Seq[MESH]
  • |Reproducibility of Results[MESH]
  • |Respiratory System/*metabolism[MESH]
  • |Smokers[MESH]
  • |Smoking Cessation[MESH]


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