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10.1183/13993003.00524-2020

http://scihub22266oqcxt.onion/10.1183/13993003.00524-2020
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32269088!7144257!32269088
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suck abstract from ncbi


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pmid32269088      Eur+Respir+J 2020 ; 55 (5): ä
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  • Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study #MMPMID32269088
  • Du RH; Liang LR; Yang CQ; Wang W; Cao TZ; Li M; Guo GY; Du J; Zheng CL; Zhu Q; Hu M; Li XY; Peng P; Shi HZ
  • Eur Respir J 2020[May]; 55 (5): ä PMID32269088show ga
  • The aim of this study was to identify factors associated with the death of patients with COVID-19 pneumonia caused by the novel coronavirus SARS-CoV-2.All clinical and laboratory parameters were collected prospectively from a cohort of patients with COVID-19 pneumonia who were hospitalised to Wuhan Pulmonary Hospital (Wuhan City, Hubei Province, China) between 25 December 2019 and 7 February 2020. Univariate and multivariate logistic regression analysis revealed that age >/=65 years (OR 3.765, 95% CI 1.146-17.394; p=0.023), pre-existing concurrent cardiovascular or cerebrovascular diseases (OR 2.464, 95% CI 0.755-8.044; p=0.007), CD3+CD8+ T-cells /=0.05 ng.mL-1 (OR 4.077, 95% CI 1.166-14.253; p<0.001) were associated with an increase in risk of mortality from COVID-19 pneumonia." has been corrected to: "Univariate and multivariate logistic regression analysis revealed that age >/=65 years (OR 3.765, 95% CI 1.201-11.803; p=0.023), pre-existing concurrent cardiovascular or cerebrovascular diseases (OR 2.464, 95% CI 1.279-4.747; p=0.007), CD3+CD8+ T-cells /=0.05 ng.mL-1 (OR 4.077, 95% CI 1.778-9.349; p<0.001) were associated with an increase in risk of mortality from COVID-19 pneumonia. In a sex-, age- and comorbid illness-matched case-control study, CD3(+)CD8(+) T-cells /=0.05 ng.mL(-1) remained as predictors for high mortality from COVID-19 pneumonia.We identified four risk factors: age >/=65 years, pre-existing concurrent cardiovascular or cerebrovascular diseases, CD3(+)CD8(+) T-cells /=0.05 ng.mL(-1) The latter two factors, especially, were predictors for mortality of COVID-19 pneumonia patients.
  • |*Coronavirus[MESH]
  • |Adult[MESH]
  • |Age Distribution[MESH]
  • |Age Factors[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Betacoronavirus[MESH]
  • |CD8-Positive T-Lymphocytes[MESH]
  • |COVID-19[MESH]
  • |Cardiovascular Diseases/epidemiology[MESH]
  • |Case-Control Studies[MESH]
  • |Cerebrovascular Disorders/epidemiology[MESH]
  • |China[MESH]
  • |Comorbidity[MESH]
  • |Coronavirus Infections/diagnosis/*mortality[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/diagnosis/*mortality/therapy[MESH]
  • |Prospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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