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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Eur+Respir+J 2020 ; 55 (5): ä Nephropedia Template TP
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Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study #MMPMID32269088
Du RH; Liang LR; Yang CQ; Wang W; Cao TZ; Li M; Guo GY; Du J; Zheng CL; Zhu Q; Hu M; Li XY; Peng P; Shi HZ
Eur Respir J 2020[May]; 55 (5): ä PMID32269088show ga
The aim of this study was to identify factors associated with the death of patients with COVID-19 pneumonia caused by the novel coronavirus SARS-CoV-2.All clinical and laboratory parameters were collected prospectively from a cohort of patients with COVID-19 pneumonia who were hospitalised to Wuhan Pulmonary Hospital (Wuhan City, Hubei Province, China) between 25 December 2019 and 7 February 2020. Univariate and multivariate logistic regression analysis revealed that age >/=65 years (OR 3.765, 95% CI 1.146-17.394; p=0.023), pre-existing concurrent cardiovascular or cerebrovascular diseases (OR 2.464, 95% CI 0.755-8.044; p=0.007), CD3+CD8+ T-cells =75 cells.muL-1 (OR 3.982, 95% CI 1.132-14.006; p<0.001) and cardiac troponin I >/=0.05 ng.mL-1 (OR 4.077, 95% CI 1.166-14.253; p<0.001) were associated with an increase in risk of mortality from COVID-19 pneumonia." has been corrected to: "Univariate and multivariate logistic regression analysis revealed that age >/=65 years (OR 3.765, 95% CI 1.201-11.803; p=0.023), pre-existing concurrent cardiovascular or cerebrovascular diseases (OR 2.464, 95% CI 1.279-4.747; p=0.007), CD3+CD8+ T-cells =75 cells.muL-1 (OR 3.982, 95% CI 1.761-9.004; p<0.001) and cardiac troponin I >/=0.05 ng.mL-1 (OR 4.077, 95% CI 1.778-9.349; p<0.001) were associated with an increase in risk of mortality from COVID-19 pneumonia. In a sex-, age- and comorbid illness-matched case-control study, CD3(+)CD8(+) T-cells =75 cells.muL(-1) and cardiac troponin I >/=0.05 ng.mL(-1) remained as predictors for high mortality from COVID-19 pneumonia.We identified four risk factors: age >/=65 years, pre-existing concurrent cardiovascular or cerebrovascular diseases, CD3(+)CD8(+) T-cells =75 cells.muL(-1) and cardiac troponin I >/=0.05 ng.mL(-1) The latter two factors, especially, were predictors for mortality of COVID-19 pneumonia patients.