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10.1073/pnas.2004999117

http://scihub22266oqcxt.onion/10.1073/pnas.2004999117
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32269081!7196762!32269081
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suck abstract from ncbi

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  • Phylogenetic network analysis of SARS-CoV-2 genomes #MMPMID32269081
  • Forster P; Forster L; Renfrew C; Forster M
  • Proc Natl Acad Sci U S A 2020[Apr]; 117 (17): 9241-9243 PMID32269081show ga
  • In a phylogenetic network analysis of 160 complete human severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) genomes, we find three central variants distinguished by amino acid changes, which we have named A, B, and C, with A being the ancestral type according to the bat outgroup coronavirus. The A and C types are found in significant proportions outside East Asia, that is, in Europeans and Americans. In contrast, the B type is the most common type in East Asia, and its ancestral genome appears not to have spread outside East Asia without first mutating into derived B types, pointing to founder effects or immunological or environmental resistance against this type outside Asia. The network faithfully traces routes of infections for documented coronavirus disease 2019 (COVID-19) cases, indicating that phylogenetic networks can likewise be successfully used to help trace undocumented COVID-19 infection sources, which can then be quarantined to prevent recurrent spread of the disease worldwide.
  • |Animals[MESH]
  • |Betacoronavirus/*genetics[MESH]
  • |COVID-19[MESH]
  • |Chiroptera/virology[MESH]
  • |Coronavirus Infections/*virology[MESH]
  • |Genome, Viral[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Phylogeny[MESH]
  • |Pneumonia, Viral/*virology[MESH]
  • |SARS Virus/genetics[MESH]
  • |SARS-CoV-2[MESH]


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  • suck abstract from ncbi

    9241 17.117 2020