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Breaking the Enigma Code of Angiotensin II Type 2 Receptor Signaling #MMPMID32268077
Sadybekov A; Katritch V
Structure 2020[Apr]; 28 (4): 390-392 PMID32268077show ga
In this issue of Structure, Asada et al. (2019) present angiotensin receptor AT(2)R structure in complex with its main endogenous agonist, AngII peptide. Complementing the previous structural studies, the new complex structure sheds light on the AT(2)R activation mechanism and opens new avenues for drug discovery targeting this enigmatic receptor.