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10.1016/j.hjc.2020.03.002 http://scihub22266oqcxt.onion/10.1016/j.hjc.2020.03.002 32251729!7194546!32251729     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Hellenic+J+Cardiol 2020 ; 61 (1): 42-45 Nephropedia Template TP {{tp|p=32251729|t=2020. The Greek study in the effects of colchicine in COvid-19 complications prevention (GRECCO-19 study): Rationale and study design |pdf=|usr=}}{{32251729}} gab.com Text The Greek study in the effects of colchicine in COvid-19 complications prevention (GRECCO-19 study): Rationale and study design JO: Hellenic J Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=32251729 #FOAvip OBJECTIVE: Colchicine has been utilized safely in a variety of cardiovascular clinical conditions. Among its potential mechanisms of action is the non-selective inhibition of NLRP3 inflammasome which is thought to be a major pathophysiologic component in the clinical course of patients with COVID-19. GRECCO-19 will be a prospective, randomized, open-labeled, controlled study to assess the effects of colchicine in COVID-19 complications prevention. METHODS: Patients with laboratory confirmed SARS-CoV-2 infection (under RT PCR) and clinical picture that involves temperature >37.5 oC and at least two out of the: i. sustained coughing, ii. sustained throat pain, iii. Anosmia and/or ageusia, iv. fatigue/tiredness, v. PaO2<95 mmHg will be included. Patients will be randomised (1:1) in colchicine or control group. RESULTS: Trial results will be disseminated through peer-reviewed publications and conference presentations. CONCLUSION: GRECCO-19 trial aims to identify whether colchicine may positively intervene in the clinical course of COVID-19. (ClinicalTrials.gov Identifier: NCT04326790). Twit Text FOAVip The Greek study in the effects of colchicine in COvid-19 complications prevention (GRECCO-19 study): Rationale and study design ????Hellenic J Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=32251729 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32251729 #FOAvip English Wikipedia <ref>{{Cite pmid|32251729}}</ref> The Greek study in the effects of colchicine in COvid-19 complications prevention (GRECCO-19 study): Rationale and study design #MMPMID32251729 Deftereos SG; Siasos G; Giannopoulos G; Vrachatis DA; Angelidis C; Giotaki SG; Gargalianos P; Giamarellou H; Gogos C; Daikos G; Lazanas M; Lagiou P; Saroglou G; Sipsas N; Tsiodras S; Chatzigeorgiou D; Moussas N; Kotanidou A; Koulouris N; Oikonomou E; Kaoukis A; Kossyvakis C; Raisakis K; Fountoulaki K; Comis M; Tsiachris D; Sarri E; Theodorakis A; Martinez-Dolz L; Sanz-Sanchez J; Reimers B; Stefanini GG; Cleman M; Filippou D; Olympios CD; Pyrgakis VN; Goudevenos J; Hahalis G; Kolettis TM; Iliodromitis E; Tousoulis D; Stefanadis C Hellenic J Cardiol 2020[Jan]; 61 (1): 42-45 PMID32251729show ga OBJECTIVE: Colchicine has been utilized safely in a variety of cardiovascular clinical conditions. Among its potential mechanisms of action is the non-selective inhibition of NLRP3 inflammasome which is thought to be a major pathophysiologic component in the clinical course of patients with COVID-19. GRECCO-19 will be a prospective, randomized, open-labeled, controlled study to assess the effects of colchicine in COVID-19 complications prevention. METHODS: Patients with laboratory confirmed SARS-CoV-2 infection (under RT PCR) and clinical picture that involves temperature >37.5 oC and at least two out of the: i. sustained coughing, ii. sustained throat pain, iii. Anosmia and/or ageusia, iv. fatigue/tiredness, v. PaO2<95 mmHg will be included. Patients will be randomised (1:1) in colchicine or control group. RESULTS: Trial results will be disseminated through peer-reviewed publications and conference presentations. CONCLUSION: GRECCO-19 trial aims to identify whether colchicine may positively intervene in the clinical course of COVID-19. (ClinicalTrials.gov Identifier: NCT04326790). |*Colchicine/administration & dosage/adverse effects[MESH] |*Coronavirus Infections/complications/diagnosis/physiopathology[MESH] |*Heart Diseases/blood/etiology/prevention & control[MESH] |*Pandemics[MESH] |*Pneumonia, Viral/complications/diagnosis/physiopathology[MESH] |Antirheumatic Agents/administration & dosage/adverse effects[MESH] |Betacoronavirus/isolation & purification[MESH] |COVID-19[MESH] |COVID-19 Testing[MESH] |Clinical Laboratory Techniques/methods[MESH] |Humans[MESH] |Randomized Controlled Trials as Topic[MESH] |SARS-CoV-2[MESH] |Symptom Assessment/methods[MESH]The Greek study in the effects of colchicine in COvid-19 complications(epmc).pdf DeepDyve Pubget Overpricing