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10.1016/j.ijid.2020.03.042

http://scihub22266oqcxt.onion/10.1016/j.ijid.2020.03.042
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32247826!7129961!32247826
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suck abstract from ncbi


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pmid32247826      Int+J+Infect+Dis 2020 ; 94 (ä): 133-138
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  • Delivery of infection from asymptomatic carriers of COVID-19 in a familial cluster #MMPMID32247826
  • Ye F; Xu S; Rong Z; Xu R; Liu X; Deng P; Liu H; Xu X
  • Int J Infect Dis 2020[May]; 94 (ä): 133-138 PMID32247826show ga
  • OBJECTIVES: With the ongoing outbreak of COVID-19 around the world, it has become a worldwide health concern. One previous study reported a family cluster with an asymptomatic transmission of COVID-19. Here, we report another series of cases and further demonstrate the repeatability of the transmission of COVID-19 by pre-symptomatic carriers. METHODS: A familial cluster of five patients associated with COVID-19 was enrolled in the hospital. We collected epidemiological and clinical characteristics, laboratory outcomes from electronic medical records, and also verified them with the patients and their families. RESULTS: Among them, three family members (Case 3/4/5) had returned from Wuhan. Additionally, two family members, those who had not traveled to Wuhan, also contracted COVID-19 after contacting with the other three family members. Case 1 developed severe pneumonia and was admitted to the ICU. Case 3 and Case 5 presented fever and cough on days two through three of hospitalization and had ground-glass opacity changes in their lungs. Case 4 presented with diarrhea and pharyngalgia after admission without radiographic abnormalities. Case 2 presented no clinical nor radiographic abnormalities. All five cases had an increasing level of C-reactive protein. CONCLUSIONS: Our findings indicate that COVID-19 can be transmitted by asymptomatic carriers during the incubation period.
  • |*Betacoronavirus[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/complications/diagnosis/*transmission[MESH]
  • |Cough/etiology[MESH]
  • |Diarrhea/etiology[MESH]
  • |Disease Outbreaks[MESH]
  • |Female[MESH]
  • |Fever/etiology[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/complications/diagnosis/*transmission[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]


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