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10.1016/j.jri.2020.103122

http://scihub22266oqcxt.onion/10.1016/j.jri.2020.103122
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32244166!7156163!32244166
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suck abstract from ncbi


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pmid32244166      J+Reprod+Immunol 2020 ; 139 (ä): 103122
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  • Why are pregnant women susceptible to COVID-19? An immunological viewpoint #MMPMID32244166
  • Liu H; Wang LL; Zhao SJ; Kwak-Kim J; Mor G; Liao AH
  • J Reprod Immunol 2020[Jun]; 139 (ä): 103122 PMID32244166show ga
  • The 2019 novel coronavirus disease (COVID-19) was first detected in December 2019 and became epidemic in Wuhan, Hubei Province, China. COVID-19 has been rapidly spreading out in China and all over the world. The virus causing COVID-19, SARS-CoV-2 has been known to be genetically similar to severe acute respiratory syndrome coronavirus (SARS-CoV) but distinct from it. Clinical manifestation of COVID-19 can be characterized by mild upper respiratory tract infection, lower respiratory tract infection involving non-life threatening pneumonia, and life-threatening pneumonia with acute respiratory distress syndrome. It affects all age groups, including newborns, to the elders. Particularly, pregnant women may be more susceptible to COVID-19 since pregnant women, in general, are vulnerable to respiratory infection. In pregnant women with COVID-19, there is no evidence for vertical transmission of the virus, but an increased prevalence of preterm deliveries has been noticed. The COVID-19 may alter immune responses at the maternal-fetal interface, and affect the well-being of mothers and infants. In this review, we focused on the reason why pregnant women are more susceptible to COVID-19 and the potential maternal and fetal complications from an immunological viewpoint.
  • |Betacoronavirus/*immunology[MESH]
  • |COVID-19[MESH]
  • |China[MESH]
  • |Coronavirus Infections/*complications/*immunology/pathology[MESH]
  • |Disease Susceptibility/*immunology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications/*immunology/pathology[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Complications, Infectious/*immunology/virology[MESH]
  • |Premature Birth/etiology[MESH]


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