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10.1002/mbo3.1036 http://scihub22266oqcxt.onion/10.1002/mbo3.1036 32239666!7349149!32239666     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32239666&cmd=llinks): Failed to open stream: HTTP request failed! 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Porcine deltacoronavirus infection alters bacterial communities in the colon and feces of neonatal piglets |pdf=|usr=}}{{32239666}} gab.com Text Porcine deltacoronavirus infection alters bacterial communities in the colon and feces of neonatal piglets JO: Microbiologyopen http://www.kidney.de/pget.php?&tw=1&pmid=32239666 #FOAvip Porcine deltacoronavirus (PDCoV) is a novel enteropathogenic coronavirus that causes watery diarrhea in piglets. Little is known regarding the alteration of the gut microbiota in PDCoV-induced diarrhea piglets. In this study, 5-day-old piglets were experimentally infected with PDCoV strain CH-01, and all piglets developed typical clinical disease, characterized by acute and severe watery diarrhea. Histologic lesions were limited to the villous epithelium of the duodenum and ileum. Gut microbiota profiles in the colon and feces of piglets inoculated with PDCoV were investigated using 16S rRNA sequencing. The results showed that PDCoV infection reduced bacterial diversity and significantly altered the composition of the microbiota from the phylum to the genus level in the colon and feces of piglets. Firmicutes (phylum), Lactobacillaceae (family), and Lactobacillus (genus) were significantly increased (p < .01), while the abundance of Bacteroidetes (phylum) was markedly reduced in the colon and feces of the PDCoV-infected piglets (p < .01) when compared to those of the healthy piglets. Furthermore, microbial function prediction indicated that the changes in the intestinal flora also affected the nucleotide transport and metabolism, defense, translation, and transcription function of the intestinal microbiota. The current study provides new insight into the pathology and physiology of PDCoV. Twit Text FOAVip Porcine deltacoronavirus infection alters bacterial communities in the colon and feces of neonatal piglets ????Microbiologyopen http://www.kidney.de/pget.php?&tw=1&pmid=32239666 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32239666 #FOAvip English Wikipedia <ref>{{Cite pmid|32239666}}</ref> Porcine deltacoronavirus infection alters bacterial communities in the colon and feces of neonatal piglets #MMPMID32239666 Li HY; Li BX; Liang QQ; Jin XH; Tang L; Ding QW; Wang ZX; Wei ZY Microbiologyopen 2020[Jul]; 9 (7): e1036 PMID32239666show ga Porcine deltacoronavirus (PDCoV) is a novel enteropathogenic coronavirus that causes watery diarrhea in piglets. Little is known regarding the alteration of the gut microbiota in PDCoV-induced diarrhea piglets. In this study, 5-day-old piglets were experimentally infected with PDCoV strain CH-01, and all piglets developed typical clinical disease, characterized by acute and severe watery diarrhea. Histologic lesions were limited to the villous epithelium of the duodenum and ileum. Gut microbiota profiles in the colon and feces of piglets inoculated with PDCoV were investigated using 16S rRNA sequencing. The results showed that PDCoV infection reduced bacterial diversity and significantly altered the composition of the microbiota from the phylum to the genus level in the colon and feces of piglets. Firmicutes (phylum), Lactobacillaceae (family), and Lactobacillus (genus) were significantly increased (p < .01), while the abundance of Bacteroidetes (phylum) was markedly reduced in the colon and feces of the PDCoV-infected piglets (p < .01) when compared to those of the healthy piglets. Furthermore, microbial function prediction indicated that the changes in the intestinal flora also affected the nucleotide transport and metabolism, defense, translation, and transcription function of the intestinal microbiota. The current study provides new insight into the pathology and physiology of PDCoV. |Animals[MESH] |Animals, Newborn[MESH] |Bacteria/*classification/genetics/isolation & purification[MESH] |Colon/*microbiology[MESH] |Coronavirus/pathogenicity[MESH] |Duodenum/*microbiology[MESH] |Feces/microbiology[MESH] |Gastroenteritis, Transmissible, of Swine/*pathology/virology[MESH] |Gastrointestinal Microbiome/*genetics[MESH] |Ileum/*microbiology[MESH] |RNA, Ribosomal, 16S/genetics[MESH] |Swine[MESH]Porcine deltacoronavirus infection alters bacterial communities in the(epmc).pdf DeepDyve Pubget Overpricing