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10.2967/jnumed.120.246256

http://scihub22266oqcxt.onion/10.2967/jnumed.120.246256
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32238429!ä!32238429

suck abstract from ncbi


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pmid32238429      J+Nucl+Med 2020 ; 61 (5): 632-636
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  • Incidental Findings Suggestive of COVID-19 in Asymptomatic Patients Undergoing Nuclear Medicine Procedures in a High-Prevalence Region #MMPMID32238429
  • Albano D; Bertagna F; Bertoli M; Bosio G; Lucchini S; Motta F; Panarotto MB; Peli A; Camoni L; Bengel FM; Giubbini R
  • J Nucl Med 2020[May]; 61 (5): 632-636 PMID32238429show ga
  • Infection with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may remain asymptomatic, leading to under-recognition of the related disease, coronavirus disease, 2019 (COVID-19), and to incidental findings in nuclear imaging procedures performed for standard clinical indications. Here, we report about our local experience in a region with high COVID-19 prevalence and dynamically increasing infection rates. Methods: Within the 8-d period of March 16-24, 2020, hybrid imaging studies of asymptomatic patients who underwent (18)F-FDG PET/CT or (131)I SPECT/CT for standard oncologic indications at our institution in Brescia, Italy, were analyzed for findings suggestive of COVID-19. The presence, radiologic features, and metabolic activity of interstitial pneumonia were identified, correlated with the subsequent short-term clinical course, and described in a case series. Results: Six of 65 patients (9%) who underwent PET/CT for various malignancies showed unexpected signs of interstitial pneumonia on CT and elevated regional (18)F-FDG avidity. Additionally, 1 of 12 patients who received radioiodine for differentiated thyroid carcinoma also showed interstitial pneumonia on SPECT/CT. Five of 7 patients had subsequent proof of COVID-19 by reverse-transcriptase polymerase chain reaction. The remaining 2 patients were not tested immediately but underwent quarantine and careful monitoring. Conclusion: Incidental findings suggestive of COVID-19 may not be infrequent in hybrid imaging of asymptomatic patients in regions with an expansive spread of SARS-CoV-2. Nuclear medicine services should prepare accordingly.
  • |*Incidental Findings[MESH]
  • |*Lung Diseases, Interstitial/diagnostic imaging/etiology[MESH]
  • |*Positron Emission Tomography Computed Tomography[MESH]
  • |Aged[MESH]
  • |Asymptomatic Diseases[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/complications/*diagnosis[MESH]
  • |Female[MESH]
  • |Fluorodeoxyglucose F18[MESH]
  • |Humans[MESH]
  • |Infection Control[MESH]
  • |Male[MESH]
  • |Membrane Glycoproteins[MESH]
  • |Middle Aged[MESH]
  • |Neoplasms/diagnostic imaging[MESH]
  • |Nuclear Medicine/trends[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/complications/*diagnosis[MESH]
  • |Prevalence[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]
  • |Tomography, Emission-Computed, Single-Photon[MESH]


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