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Investigation of an epidemic cluster caused by COVID rectangle19 cases in incubation period in Shanghai #MMPMID32234128
Xiao WJ; Gao Q; Jin K; Gong XH; Han RB; Jiang CY; Jiang XJ; Jin BH; Fang QW; Pan H; Wu HY; Sun XD
Zhonghua Liu Xing Bing Xue Za Zhi 2020[Apr]; 41 (ä): E033 PMID32234128show ga
Objective: To analyze the epidemiological characteristics of a cluster of 5 confirmed COVID rectangle19 cases related with the transmission in incubation period of initial case, and find out the infection source and transmission chain.. Methods: According to "The Prevention and Control Protocol for Coronavirus Disease 2019 (Third Edition)" issued by the National Health Commission, a field epidemiological survey was conducted for the 5 cases in January 2020. Nasopharyngeal swabs and sputum samples were collected from them for the detection of 2019-nCoV by real time RT-PCR. Multi prevention and control measures were taken, such as tracking and screening close contacts, medical isolation observation, investigating the epidemiological link, analyzing transmission chain. Results: Case 1, who had common environmental exposure with other COVID rectangle19 cases, got sick on 20 January, 2020 and was confirmed on 1 February. Case 2 became symptomatic on 22 January and was confirmed on 27 January. Case 3 got sick on 25 January and was confirmed on 30 January. Case 4 had illness onset on 20 January and was confirmed on 1 February. Case 5 got sick on 23 January and was confirmed on 31 January. Among the 5 cases, case 2 died and the illness of other cases were effectively controlled. After exclusion of other common exposure factors, case 1 had a 6-hour meeting with case 2 and case 3 on 19 January. Case 2 and case 3 might be infected by case 1 during the incubation period. It is the key point for epidemiological investigation. Conclusion: The epidemiological investigation indicates that the transmission might occur in the incubation period of COVID-19 case, close attention should be paid to it in future COVID-19 prevention and control.
Zhonghua+Liu+Xing+Bing+Xue+Za+Zhi 2020 ; 41 (ä): E033
