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10.1002/jmv.25804

http://scihub22266oqcxt.onion/10.1002/jmv.25804
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32232976!ä!32232976

suck abstract from ncbi


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pmid32232976      J+Med+Virol 2020 ; 92 (10): 1721-1723
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  • CD-sACE2 inclusion compounds: An effective treatment for coronavirus disease 2019 (COVID-19) #MMPMID32232976
  • Sun P; Lu X; Xu C; Wang Y; Sun W; Xi J
  • J Med Virol 2020[Oct]; 92 (10): 1721-1723 PMID32232976show ga
  • Coronaviruses are common human viruses and include the severe acute respiratory syndrome coronavirus (SARS-CoV), the middle east respiratory syndrome coronavirus and the SARS-CoV-2. Coronaviruses mainly bind to transmembrane receptor proteins on the human cell membrane through spike proteins (S-proteins), thus releasing the RNA of the virus into the interior of the host cell to cause an infection. In this article, we discuss the mechanism and production of cyclodextrin-soluble angiotensin-converting enzyme 2 (CD-sACE2) inclusion compounds in the treatment of SARS-CoV-2 infections by blocking S-proteins. On the basis of the current research evidence, we believe that CD-sACE2 inclusion compounds have the potential to treat COVID-19. We hope that our article can provide a theoretical basis for later experiments.
  • |*COVID-19 Drug Treatment[MESH]
  • |Angiotensin-Converting Enzyme 2/*metabolism[MESH]
  • |COVID-19/*metabolism[MESH]
  • |Cyclodextrins/*therapeutic use[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/drug therapy/metabolism/virology[MESH]
  • |SARS-CoV-2/drug effects[MESH]


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