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10.1152/ajpendo.00124.2020

http://scihub22266oqcxt.onion/10.1152/ajpendo.00124.2020
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32228322!7191633!32228322
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suck abstract from ncbi


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pmid32228322      Am+J+Physiol+Endocrinol+Metab 2020 ; 318 (5): E736-E741
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  • COVID-19 pandemic, coronaviruses, and diabetes mellitus #MMPMID32228322
  • Muniyappa R; Gubbi S
  • Am J Physiol Endocrinol Metab 2020[May]; 318 (5): E736-E741 PMID32228322show ga
  • The pandemic of coronavirus disease (COVID-19), a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is causing substantial morbidity and mortality. Older age and presence of diabetes mellitus, hypertension, and obesity significantly increases the risk for hospitalization and death in COVID-19 patients. In this Perspective, informed by the studies on SARS-CoV-2, Middle East respiratory syndrome (MERS-CoV), and the current literature on SARS-CoV-2, we discuss potential mechanisms by which diabetes modulates the host-viral interactions and host-immune responses. We hope to highlight gaps in knowledge that require further studies pertinent to COVID-19 in patients with diabetes.
  • |*Betacoronavirus/immunology/pathogenicity[MESH]
  • |*Coronavirus Infections/immunology/mortality/physiopathology/virology[MESH]
  • |*Diabetes Mellitus/immunology/mortality[MESH]
  • |*Host Microbial Interactions/immunology[MESH]
  • |*Pandemics[MESH]
  • |*Pneumonia, Viral/immunology/mortality/physiopathology/virology[MESH]
  • |Animals[MESH]
  • |COVID-19[MESH]
  • |Humans[MESH]
  • |Risk Assessment[MESH]
  • |SARS-CoV-2[MESH]
  • |Uncertainty[MESH]


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