Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1093/infdis/jiaa150 http://scihub22266oqcxt.onion/10.1093/infdis/jiaa150 32227123!7184346!32227123     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Infect+Dis 2020 ; 221 (11): 1762-1769 Nephropedia Template TP {{tp|p=32227123|t=2020. Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia |pdf=|usr=}}{{32227123}} gab.com Text Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia JO: J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32227123 #FOAvip BACKGROUND: In December 2019, novel coronavirus (SARS-CoV-2) pneumonia (COVID-19) was reported in Wuhan and has since rapidly spread throughout China. We aimed to clarify the characteristics and clinical significance of peripheral lymphocyte subset alteration in COVID-19. METHODS: The levels of peripheral lymphocyte subsets were measured by flow cytometry in 60 hospitalized COVID-19 patients before and after treatment, and their association with clinical characteristics and treatment efficacy was analyzed. RESULTS: Total lymphocytes, CD4+ T cells, CD8+ T cells, B cells, and natural killer (NK) cells decreased in COVID-19 patients, and severe cases had a lower level than mild cases. The subsets showed a significant association with inflammatory status in COVID-19, especially CD8+ T cells and CD4+/CD8+ ratio. After treatment, 37 patients (67%) showed clinical response, with an increase in CD8+ T cells and B cells. No significant change in any subset was detected in nonresponsive cases. In multivariate analysis, posttreatment decrease in CD8+ T cells and B cells and increase in CD4+/CD8+ ratio were indicated as independent predictors of poor efficacy. CONCLUSIONS: Peripheral lymphocyte subset alteration was associated with clinical characteristics and treatment efficacy of COVID-19. CD8+ T cells tended to be an independent predictor for COVID-19 severity and treatment efficacy. Twit Text FOAVip Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia ????J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32227123 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32227123 #FOAvip English Wikipedia <ref>{{Cite pmid|32227123}}</ref> Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia #MMPMID32227123 Wang F; Nie J; Wang H; Zhao Q; Xiong Y; Deng L; Song S; Ma Z; Mo P; Zhang Y J Infect Dis 2020[May]; 221 (11): 1762-1769 PMID32227123show ga BACKGROUND: In December 2019, novel coronavirus (SARS-CoV-2) pneumonia (COVID-19) was reported in Wuhan and has since rapidly spread throughout China. We aimed to clarify the characteristics and clinical significance of peripheral lymphocyte subset alteration in COVID-19. METHODS: The levels of peripheral lymphocyte subsets were measured by flow cytometry in 60 hospitalized COVID-19 patients before and after treatment, and their association with clinical characteristics and treatment efficacy was analyzed. RESULTS: Total lymphocytes, CD4+ T cells, CD8+ T cells, B cells, and natural killer (NK) cells decreased in COVID-19 patients, and severe cases had a lower level than mild cases. The subsets showed a significant association with inflammatory status in COVID-19, especially CD8+ T cells and CD4+/CD8+ ratio. After treatment, 37 patients (67%) showed clinical response, with an increase in CD8+ T cells and B cells. No significant change in any subset was detected in nonresponsive cases. In multivariate analysis, posttreatment decrease in CD8+ T cells and B cells and increase in CD4+/CD8+ ratio were indicated as independent predictors of poor efficacy. CONCLUSIONS: Peripheral lymphocyte subset alteration was associated with clinical characteristics and treatment efficacy of COVID-19. CD8+ T cells tended to be an independent predictor for COVID-19 severity and treatment efficacy. |*Lymphocyte Subsets/immunology[MESH] |Adult[MESH] |Aged[MESH] |Betacoronavirus/isolation & purification[MESH] |COVID-19[MESH] |China[MESH] |Coronavirus Infections/*complications/diagnosis/*physiopathology/therapy[MESH] |Female[MESH] |Flow Cytometry[MESH] |Humans[MESH] |Lymphocyte Count[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Pneumonia, Viral/*complications/diagnosis/*physiopathology/therapy[MESH] |Pneumonia/diagnosis/*etiology/*physiopathology/therapy[MESH] |Prognosis[MESH] |SARS-CoV-2[MESH]Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19(epmc).pdf DeepDyve Pubget Overpricing