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10.1016/j.chest.2020.03.032 http://scihub22266oqcxt.onion/10.1016/j.chest.2020.03.032 32224074!7151343!32224074     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Chest 2020 ; 158 (1): 195-205 Nephropedia Template TP {{tp|p=32224074|t=2020. Comparison of Hospitalized Patients With ARDS Caused by COVID-19 and H1N1 |pdf=|usr=}}{{32224074}} gab.com Text Comparison of Hospitalized Patients With ARDS Caused by COVID-19 and H1N1 JO: Chest http://www.kidney.de/pget.php?&tw=1&pmid=32224074 #FOAvip BACKGROUND: Since the outbreak of coronavirus disease 2019 (COVID-19) in China in December 2019, considerable attention has been focused on its elucidation. However, it is also important for clinicians and epidemiologists to differentiate COVID-19 from other respiratory infectious diseases such as influenza viruses. RESEARCH QUESTION: The aim of this study was to explore the different clinical presentations between COVID-19 and influenza A (H1N1) pneumonia in patients with ARDS. STUDY DESIGN AND METHODS: This analysis was a retrospective case-control study. Two independent cohorts of patients with ARDS infected with either COVID-19 (n = 73) or H1N1 (n = 75) were compared. Their clinical manifestations, imaging characteristics, treatments, and prognosis were analyzed and compared. RESULTS: The median age of patients with COVID-19 was higher than that of patients with H1N1, and there was a higher proportion of male subjects among the H1N1 cohort (P < .05). Patients with COVID-19 exhibited higher proportions of nonproductive coughs, fatigue, and GI symptoms than those of patients with H1N1 (P < .05). Patients with H1N1 had higher Sequential Organ Failure Assessment (SOFA) scores than patients with COVID-19 (P < .05). The Pao(2)/Fio(2) of 198.5 mm Hg in the COVID-19 cohort was significantly higher than the Pao(2)/Fio(2) of 107.0 mm Hg in the H1N1 cohort (P < .001). Ground-glass opacities was more common in patients with COVID-19 than in patients with H1N1 (P < .001). There was a greater variety of antiviral therapies administered to COVID-19 patients than to H1N1 patients. The in-hospital mortality of patients with COVID-19 was 28.8%, whereas that of patients with H1N1 was 34.7% (P = .483). SOFA score-adjusted mortality of H1N1 patients was significantly higher than that of COVID-19 patients, with a rate ratio of 2.009 (95% CI, 1.563-2.583; P < .001). INTERPRETATION: There were many differences in clinical presentations between patients with ARDS infected with either COVID-19 or H1N1. Compared with H1N1 patients, patients with COVID-19-induced ARDS had lower severity of illness scores at presentation and lower SOFA score-adjusted mortality. Twit Text FOAVip Comparison of Hospitalized Patients With ARDS Caused by COVID-19 and H1N1 ????Chest http://www.kidney.de/pget.php?&tw=1&pmid=32224074 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32224074 #FOAvip English Wikipedia <ref>{{Cite pmid|32224074}}</ref> Comparison of Hospitalized Patients With ARDS Caused by COVID-19 and H1N1 #MMPMID32224074 Tang X; Du RH; Wang R; Cao TZ; Guan LL; Yang CQ; Zhu Q; Hu M; Li XY; Li Y; Liang LR; Tong ZH; Sun B; Peng P; Shi HZ Chest 2020[Jul]; 158 (1): 195-205 PMID32224074show ga BACKGROUND: Since the outbreak of coronavirus disease 2019 (COVID-19) in China in December 2019, considerable attention has been focused on its elucidation. However, it is also important for clinicians and epidemiologists to differentiate COVID-19 from other respiratory infectious diseases such as influenza viruses. RESEARCH QUESTION: The aim of this study was to explore the different clinical presentations between COVID-19 and influenza A (H1N1) pneumonia in patients with ARDS. STUDY DESIGN AND METHODS: This analysis was a retrospective case-control study. Two independent cohorts of patients with ARDS infected with either COVID-19 (n = 73) or H1N1 (n = 75) were compared. Their clinical manifestations, imaging characteristics, treatments, and prognosis were analyzed and compared. RESULTS: The median age of patients with COVID-19 was higher than that of patients with H1N1, and there was a higher proportion of male subjects among the H1N1 cohort (P < .05). Patients with COVID-19 exhibited higher proportions of nonproductive coughs, fatigue, and GI symptoms than those of patients with H1N1 (P < .05). Patients with H1N1 had higher Sequential Organ Failure Assessment (SOFA) scores than patients with COVID-19 (P < .05). The Pao(2)/Fio(2) of 198.5 mm Hg in the COVID-19 cohort was significantly higher than the Pao(2)/Fio(2) of 107.0 mm Hg in the H1N1 cohort (P < .001). Ground-glass opacities was more common in patients with COVID-19 than in patients with H1N1 (P < .001). There was a greater variety of antiviral therapies administered to COVID-19 patients than to H1N1 patients. The in-hospital mortality of patients with COVID-19 was 28.8%, whereas that of patients with H1N1 was 34.7% (P = .483). SOFA score-adjusted mortality of H1N1 patients was significantly higher than that of COVID-19 patients, with a rate ratio of 2.009 (95% CI, 1.563-2.583; P < .001). INTERPRETATION: There were many differences in clinical presentations between patients with ARDS infected with either COVID-19 or H1N1. Compared with H1N1 patients, patients with COVID-19-induced ARDS had lower severity of illness scores at presentation and lower SOFA score-adjusted mortality. |*Coronavirus Infections/diagnosis/mortality/physiopathology[MESH] |*Hospital Mortality[MESH] |*Influenza, Human/diagnosis/mortality/physiopathology[MESH] |*Pandemics[MESH] |*Pneumonia, Viral/diagnosis/mortality/physiopathology[MESH] |*Symptom Assessment/methods/statistics & numerical data[MESH] |Age Factors[MESH] |Antiviral Agents/therapeutic use[MESH] |Betacoronavirus/*isolation & purification[MESH] |COVID-19[MESH] |Case-Control Studies[MESH] |China/epidemiology[MESH] |Diagnosis, Differential[MESH] |Female[MESH] |Humans[MESH] |Influenza A Virus, H1N1 Subtype/*isolation & purification[MESH] |Male[MESH] |Middle Aged[MESH] |Organ Dysfunction Scores[MESH] |Prognosis[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH]Comparison of Hospitalized Patients With ARDS Caused by COVID-19 and H(epmc).pdf DeepDyve Pubget Overpricing