Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Nature 2020 ; 583 (7815): 282-285 Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins #MMPMID32218527
Lam TT; Jia N; Zhang YW; Shum MH; Jiang JF; Zhu HC; Tong YG; Shi YX; Ni XB; Liao YS; Li WJ; Jiang BG; Wei W; Yuan TT; Zheng K; Cui XM; Li J; Pei GQ; Qiang X; Cheung WY; Li LF; Sun FF; Qin S; Huang JC; Leung GM; Holmes EC; Hu YL; Guan Y; Cao WC
Nature 2020[Jul]; 583 (7815): 282-285 PMID32218527show ga
The ongoing outbreak of viral pneumonia in China and across the world is associated with a new coronavirus, SARS-CoV-2(1). This outbreak has been tentatively associated with a seafood market in Wuhan, China, where the sale of wild animals may be the source of zoonotic infection(2). Although bats are probable reservoir hosts for SARS-CoV-2, the identity of any intermediate host that may have facilitated transfer to humans is unknown. Here we report the identification of SARS-CoV-2-related coronaviruses in Malayan pangolins (Manis javanica) seized in anti-smuggling operations in southern China. Metagenomic sequencing identified pangolin-associated coronaviruses that belong to two sub-lineages of SARS-CoV-2-related coronaviruses, including one that exhibits strong similarity in the receptor-binding domain to SARS-CoV-2. The discovery of multiple lineages of pangolin coronavirus and their similarity to SARS-CoV-2 suggests that pangolins should be considered as possible hosts in the emergence of new coronaviruses and should be removed from wet markets to prevent zoonotic transmission.
Nature 2020 ; 583 (7815): 282-285
