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10.3390/v12040360 http://scihub22266oqcxt.onion/10.3390/v12040360 32218151!7232164!32218151     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Viruses 2020 ; 12 (4): ä Nephropedia Template TP {{tp|p=32218151|t=2020. Structural Genomics of SARS-CoV-2 Indicates Evolutionary Conserved Functional Regions of Viral Proteins |pdf=|usr=}}{{32218151}} gab.com Text Structural Genomics of SARS-CoV-2 Indicates Evolutionary Conserved Functional Regions of Viral Proteins JO: Viruses http://www.kidney.de/pget.php?&tw=1&pmid=32218151 #FOAvip During its first two and a half months, the recently emerged 2019 novel coronavirus, SARS-CoV-2, has already infected over one-hundred thousand people worldwide and has taken more than four thousand lives. However, the swiftly spreading virus also caused an unprecedentedly rapid response from the research community facing the unknown health challenge of potentially enormous proportions. Unfortunately, the experimental research to understand the molecular mechanisms behind the viral infection and to design a vaccine or antivirals is costly and takes months to develop. To expedite the advancement of our knowledge, we leveraged data about the related coronaviruses that is readily available in public databases and integrated these data into a single computational pipeline. As a result, we provide comprehensive structural genomics and interactomics roadmaps of SARS-CoV-2 and use this information to infer the possible functional differences and similarities with the related SARS coronavirus. All data are made publicly available to the research community. Twit Text FOAVip Structural Genomics of SARS-CoV-2 Indicates Evolutionary Conserved Functional Regions of Viral Proteins ????Viruses http://www.kidney.de/pget.php?&tw=1&pmid=32218151 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32218151 #FOAvip English Wikipedia <ref>{{Cite pmid|32218151}}</ref> Structural Genomics of SARS-CoV-2 Indicates Evolutionary Conserved Functional Regions of Viral Proteins #MMPMID32218151 Srinivasan S; Cui H; Gao Z; Liu M; Lu S; Mkandawire W; Narykov O; Sun M; Korkin D Viruses 2020[Mar]; 12 (4): ä PMID32218151show ga During its first two and a half months, the recently emerged 2019 novel coronavirus, SARS-CoV-2, has already infected over one-hundred thousand people worldwide and has taken more than four thousand lives. However, the swiftly spreading virus also caused an unprecedentedly rapid response from the research community facing the unknown health challenge of potentially enormous proportions. Unfortunately, the experimental research to understand the molecular mechanisms behind the viral infection and to design a vaccine or antivirals is costly and takes months to develop. To expedite the advancement of our knowledge, we leveraged data about the related coronaviruses that is readily available in public databases and integrated these data into a single computational pipeline. As a result, we provide comprehensive structural genomics and interactomics roadmaps of SARS-CoV-2 and use this information to infer the possible functional differences and similarities with the related SARS coronavirus. All data are made publicly available to the research community. |Animals[MESH] |Betacoronavirus/chemistry/*genetics[MESH] |Binding Sites[MESH] |Biological Evolution[MESH] |COVID-19[MESH] |Chiroptera/virology[MESH] |Computational Biology[MESH] |Conserved Sequence[MESH] |Coronavirus Infections[MESH] |Coronavirus Nucleocapsid Proteins[MESH] |Genome, Viral[MESH] |Genomics[MESH] |Humans[MESH] |Ligands[MESH] |Models, Molecular[MESH] |Nucleocapsid Proteins/chemistry[MESH] |Pandemics[MESH] |Phosphoproteins[MESH] |Phylogeny[MESH] |Pneumonia, Viral[MESH] |Protein Interaction Mapping[MESH] |Protein Structure, Tertiary[MESH] |SARS-CoV-2[MESH] |Sequence Alignment[MESH] |Severe acute respiratory syndrome-related coronavirus[MESH] |Spike Glycoprotein, Coronavirus/chemistry[MESH] |Viral Envelope Proteins/chemistry[MESH] |Viral Matrix Proteins/chemistry[MESH]Structural Genomics of SARS-CoV-2 Indicates Evolutionary Conserved Fun(epmc).pdf DeepDyve Pubget Overpricing