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10.1172/JCI137647 http://scihub22266oqcxt.onion/10.1172/JCI137647 32217834!7190904!32217834     free     free     free       J+Clin+Invest 2020 ; 130 (5): 2202-2205 Nephropedia Template TP {{tp|p=32217834|t=2020. SARS-CoV-2: a storm is raging |pdf=|usr=}}{{32217834}} gab.com Text SARS-CoV-2: a storm is raging JO: J Clin Invest http://www.kidney.de/pget.php?&tw=1&pmid=32217834 #FOAvip The pandemic coronavirus infectious disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading across the globe. In this issue of the JCI, Chen and colleagues compared the clinical and immunological characteristics between moderate and severe COVID-19. The authors found that respiratory distress on admission is associated with unfavorable outcomes. Increased cytokine levels (IL-6, IL-10, and TNF-alpha), lymphopenia (in CD4+ and CD8+ T cells), and decreased IFN-gamma expression in CD4+ T cells are associated with severe COVID-19. Overall, this study characterized the cytokine storm in severe COVID-19 and provides insights into immune therapeutics and vaccine design. Twit Text FOAVip SARS-CoV-2: a storm is raging ????J Clin Invest http://www.kidney.de/pget.php?&tw=1&pmid=32217834 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32217834 #FOAvip English Wikipedia <ref>{{Cite pmid|32217834}}</ref> SARS-CoV-2: a storm is raging #MMPMID32217834 Pedersen SF; Ho YC J Clin Invest 2020[May]; 130 (5): 2202-2205 PMID32217834show ga The pandemic coronavirus infectious disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading across the globe. In this issue of the JCI, Chen and colleagues compared the clinical and immunological characteristics between moderate and severe COVID-19. The authors found that respiratory distress on admission is associated with unfavorable outcomes. Increased cytokine levels (IL-6, IL-10, and TNF-alpha), lymphopenia (in CD4+ and CD8+ T cells), and decreased IFN-gamma expression in CD4+ T cells are associated with severe COVID-19. Overall, this study characterized the cytokine storm in severe COVID-19 and provides insights into immune therapeutics and vaccine design. |Age Factors[MESH] |Betacoronavirus/*immunology[MESH] |COVID-19[MESH] |Coronavirus Infections/complications/*immunology/physiopathology/virology[MESH] |Cytokines/blood/*immunology[MESH] |Disease Progression[MESH] |Humans[MESH] |Lymphocytes/cytology/immunology[MESH] |Pandemics[MESH] |Pneumonia, Viral/complications/*immunology/physiopathology/virology[MESH] |Respiratory Distress Syndrome/etiology[MESH] |SARS-CoV-2[MESH]SARS-CoV-2: a storm is raging (epmc).pdf DeepDyve Pubget Overpricing