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10.3201/eid2606.200037 http://scihub22266oqcxt.onion/10.3201/eid2606.200037 32213260!7258456!32213260     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Emerg+Infect+Dis 2020 ; 26 (6): 1102-1112 Nephropedia Template TP {{tp|p=32213260|t=2020. Pharmacologic Treatments and Supportive Care for Middle East Respiratory Syndrome |pdf=|usr=}}{{32213260}} gab.com Text Pharmacologic Treatments and Supportive Care for Middle East Respiratory Syndrome JO: Emerg Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32213260 #FOAvip Available animal and cell line models have suggested that specific therapeutics might be effective in treating Middle East respiratory syndrome (MERS). We conducted a systematic review of evidence for treatment with pharmacologic and supportive therapies. We developed a protocol and searched 5 databases for studies describing treatment of MERS and deaths in MERS patients. Risk of bias (RoB) was assessed by using ROBINS-I tool. We retrieved 3,660 unique citations; 20 observational studies met eligibility, and we studied 13 therapies. Most studies were at serious or critical RoB; no studies were at low RoB. One study, at moderate RoB, showed reduced mortality rates in severe MERS patients with extracorporeal membrane oxygenation; no other studies showed a significant lifesaving benefit to any treatment. The existing literature on treatments for MERS is observational and at moderate to critical RoB. Clinical trials are needed to guide treatment decisions. Twit Text FOAVip Pharmacologic Treatments and Supportive Care for Middle East Respiratory Syndrome ????Emerg Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32213260 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32213260 #FOAvip English Wikipedia <ref>{{Cite pmid|32213260}}</ref> Pharmacologic Treatments and Supportive Care for Middle East Respiratory Syndrome #MMPMID32213260 Kain T; Lindsay PJ; Adhikari NKJ; Arabi YM; Van Kerkhove MD; Fowler RA Emerg Infect Dis 2020[Jun]; 26 (6): 1102-1112 PMID32213260show ga Available animal and cell line models have suggested that specific therapeutics might be effective in treating Middle East respiratory syndrome (MERS). We conducted a systematic review of evidence for treatment with pharmacologic and supportive therapies. We developed a protocol and searched 5 databases for studies describing treatment of MERS and deaths in MERS patients. Risk of bias (RoB) was assessed by using ROBINS-I tool. We retrieved 3,660 unique citations; 20 observational studies met eligibility, and we studied 13 therapies. Most studies were at serious or critical RoB; no studies were at low RoB. One study, at moderate RoB, showed reduced mortality rates in severe MERS patients with extracorporeal membrane oxygenation; no other studies showed a significant lifesaving benefit to any treatment. The existing literature on treatments for MERS is observational and at moderate to critical RoB. Clinical trials are needed to guide treatment decisions. |*Middle East Respiratory Syndrome Coronavirus[MESH] |Antiviral Agents/*therapeutic use[MESH] |Coronavirus Infections/*drug therapy/virology[MESH]Pharmacologic Treatments and Supportive Care for Middle East Respirato(epmc).pdf DeepDyve Pubget Overpricing