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10.12116/j.issn.1004-5619.2020.02.002 http://scihub22266oqcxt.onion/10.12116/j.issn.1004-5619.2020.02.002 32212512!ä!32212512 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Fa+Yi+Xue+Za+Zhi 2020 ; 36 (2): 157-163 Nephropedia Template TP {{tp|p=32212512|t=2020. Trial of Chloroquines in the Treatment of COVID-19 and Its Research Progress in Forensic Toxicology |pdf=|usr=}}{{32212512}} gab.com Text Trial of Chloroquines in the Treatment of COVID-19 and Its Research Progress in Forensic Toxicology JO: Fa Yi Xue Za Zhi http://www.kidney.de/pget.php?&tw=1&pmid=32212512 #FOAvip Chloroquines are the long-established prescription drug, which are often used clinically to treat malaria and connective tissue diseases. Since December 2019, corona virus disease 2019 ?COVID-19? outbreaks caused by 2019 novel coronavirus ?2019-nCoV? has occurred in China and many countries around the world. Due to the lack of drugs against COVID-19, the disease spreads rapidly and the mortality rate is relatively high. Therefore, specific drugs against 2019-nCoV need to be quickly screened. The antimalarial drug chloroquine phosphate which has already been approved is confirmed to have an anti-2019-nCoV effect and has been included in diagnostic and therapeutic guidelines. However, awareness of the risk of chloroquine phosphate causing acute poisoning or even death should be strengthened. The current dosage recommended in clinical treatment is larger than that in previous treatment of malaria and the period of treatment is longer. Many provinces have required close clinical monitoring of adverse reactions. This paper reviews the pharmacological effects, poisoning and toxicological mechanisms, in vivo metabolism and distribution, and forensic issues of chloroquine drugs, in order to provide help to forensic practice and clinical work. Twit Text FOAVip Trial of Chloroquines in the Treatment of COVID-19 and Its Research Progress in Forensic Toxicology ????Fa Yi Xue Za Zhi http://www.kidney.de/pget.php?&tw=1&pmid=32212512 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32212512 #FOAvip English Wikipedia <ref>{{Cite pmid|32212512}}</ref> Trial of Chloroquines in the Treatment of COVID-19 and Its Research Progress in Forensic Toxicology #MMPMID32212512 Duan YJ; Liu Q; Zhao SQ; Huang F; Ren L; Liu L; Zhou YW Fa Yi Xue Za Zhi 2020[Apr]; 36 (2): 157-163 PMID32212512show ga Chloroquines are the long-established prescription drug, which are often used clinically to treat malaria and connective tissue diseases. Since December 2019, corona virus disease 2019 ?COVID-19? outbreaks caused by 2019 novel coronavirus ?2019-nCoV? has occurred in China and many countries around the world. Due to the lack of drugs against COVID-19, the disease spreads rapidly and the mortality rate is relatively high. Therefore, specific drugs against 2019-nCoV need to be quickly screened. The antimalarial drug chloroquine phosphate which has already been approved is confirmed to have an anti-2019-nCoV effect and has been included in diagnostic and therapeutic guidelines. However, awareness of the risk of chloroquine phosphate causing acute poisoning or even death should be strengthened. The current dosage recommended in clinical treatment is larger than that in previous treatment of malaria and the period of treatment is longer. Many provinces have required close clinical monitoring of adverse reactions. This paper reviews the pharmacological effects, poisoning and toxicological mechanisms, in vivo metabolism and distribution, and forensic issues of chloroquine drugs, in order to provide help to forensic practice and clinical work. |Betacoronavirus[MESH] |COVID-19[MESH] |COVID-19 Drug Treatment[MESH] |China[MESH] |Chloroquine/*adverse effects/*therapeutic use[MESH] |Coronavirus Infections/*drug therapy[MESH] |Forensic Toxicology[MESH] |Humans[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy[MESH]Trial of Chloroquines in the Treatment of COVID-19 and Its Research Pr(epmc).pdf DeepDyve Pubget Overpricing