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10.1128/AAC.00440-20

http://scihub22266oqcxt.onion/10.1128/AAC.00440-20
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32205350!7179581!32205350
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suck abstract from ncbi


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pmid32205350      Antimicrob+Agents+Chemother 2020 ; 64 (5): ä
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  • Tilorone, a Broad-Spectrum Antiviral for Emerging Viruses #MMPMID32205350
  • Ekins S; Madrid PB
  • Antimicrob Agents Chemother 2020[Apr]; 64 (5): ä PMID32205350show ga
  • Tilorone is a 50-year-old synthetic small-molecule compound with antiviral activity that is proposed to induce interferon after oral administration. This drug is used as a broad-spectrum antiviral in several countries of the Russian Federation. We have recently described activity in vitro and in vivo against the Ebola virus. After a broad screening of additional viruses, we now describe in vitro activity against Chikungunya virus (CHIK) and Middle Eastern respiratory syndrome coronavirus (MERS-CoV).
  • |Antiviral Agents/*pharmacology[MESH]
  • |Chikungunya virus/*drug effects[MESH]
  • |Communicable Diseases, Emerging/*drug therapy[MESH]
  • |Coronavirus/*drug effects[MESH]
  • |Ebolavirus/*drug effects[MESH]
  • |Humans[MESH]
  • |Middle East Respiratory Syndrome Coronavirus/*drug effects[MESH]


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