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10.1016/j.jmii.2020.03.005

http://scihub22266oqcxt.onion/10.1016/j.jmii.2020.03.005
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32205092!7156211!32205092
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suck abstract from ncbi

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  • TH17 responses in cytokine storm of COVID-19: An emerging target of JAK2 inhibitor Fedratinib #MMPMID32205092
  • Wu D; Yang XO
  • J Microbiol Immunol Infect 2020[Jun]; 53 (3): 368-370 PMID32205092show ga
  • COVID-19 emerges as a pandemic disease with high mortality. Development of effective prevention and treatment is an urgent need. We reviewed TH17 responses in patients with SARS-CoV-2 and proposed an FDA approved JAK2 inhibitor Fedratinib for reducing mortality of patients with TH17 type immune profiles.
  • |Betacoronavirus/immunology[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*drug therapy/pathology[MESH]
  • |Cytokine Release Syndrome/*drug therapy[MESH]
  • |Cytokines/biosynthesis/immunology[MESH]
  • |Humans[MESH]
  • |Janus Kinase 2/*antagonists & inhibitors[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy/pathology[MESH]
  • |Pyrrolidines/*pharmacology[MESH]
  • |SARS-CoV-2[MESH]
  • |Sulfonamides/*pharmacology[MESH]
  • |Th17 Cells/*immunology[MESH]


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  • suck abstract from ncbi

    368 3.53 2020