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10.1016/j.jamda.2020.01.111 http://scihub22266oqcxt.onion/10.1016/j.jamda.2020.01.111 32199718!ä!32199718 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32199718&cmd=llinks): Failed to open stream: HTTP request failed! 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Impact of an Antimicrobial Stewardship Program on Resistance to Fluoroquinolones of Urinary Enterobacteriaceae Isolated From Nursing Home Residents: A Retrospective Cohort Study |pdf=|usr=}}{{32199718}} gab.com Text Impact of an Antimicrobial Stewardship Program on Resistance to Fluoroquinolones of Urinary Enterobacteriaceae Isolated From Nursing Home Residents: A Retrospective Cohort Study JO: J Am Med Dir Assoc http://www.kidney.de/pget.php?&tw=1&pmid=32199718 #FOAvip OBJECTIVES: This study investigated the impact of an antimicrobial stewardship program on fluoroquinolone (FLQ) resistance in urinary Enterobacteriaceae isolated from residents of 3 French nursing homes. DESIGN: A multicentric retrospective before-and-after study was conducted. SETTING AND PARTICIPANTS: All the first urinary Enterobacteriaceae isolates obtained from nursing home residents were included. Two time frames were analyzed: 2013-2015 and 2016-2017. METHODS: The antimicrobial stewardship program started in 2015 and was based on (1) 1-day training for use of an "antimicrobial stewardship kit for nursing homes;" and (2) daily support and training of the coordinating physician by an antibiotic mobile team (AMT) in 2 of 3 nursing homes. RESULTS: Overall, 338 urinary isolates were analyzed. Escherichia coli was the most frequent species (212/338, 63%). A significant reduction of resistance to ofloxacin was observed between 2013-2015 and 2016-2017 in general (Delta = -16%, P = .004) and among isolates obtained from patients hospitalized in the county nursing home with AMT support (Delta = -28%, P < .01). A nonstatistically significant reduction in ofloxacin resistance was also observed in the hospital nursing home with AMT support (Delta = -18%, P = .06). CONCLUSIONS AND IMPLICATIONS: Our antimicrobial stewardship program resulted in a decrease in resistance to FLQ among urinary Enterobacteriaceae isolated from nursing home residents. The support of an AMT along with continuous training of the coordinating physician seems to be an important component to ensure efficacy of the intervention. Twit Text FOAVip Impact of an Antimicrobial Stewardship Program on Resistance to Fluoroquinolones of Urinary Enterobacteriaceae Isolated From Nursing Home Residents: A Retrospective Cohort Study ????J Am Med Dir Assoc http://www.kidney.de/pget.php?&tw=1&pmid=32199718 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32199718 #FOAvip English Wikipedia <ref>{{Cite pmid|32199718}}</ref> Impact of an Antimicrobial Stewardship Program on Resistance to Fluoroquinolones of Urinary Enterobacteriaceae Isolated From Nursing Home Residents: A Retrospective Cohort Study #MMPMID32199718 Strazzulla A; Bokobza S; Ombandza E; Kherallah K; Hommel S; Draidi R; Bonutto C; Zamponi DB; Gauzit R; Diamantis S J Am Med Dir Assoc 2020[Sep]; 21 (9): 1322-1326 PMID32199718show ga OBJECTIVES: This study investigated the impact of an antimicrobial stewardship program on fluoroquinolone (FLQ) resistance in urinary Enterobacteriaceae isolated from residents of 3 French nursing homes. DESIGN: A multicentric retrospective before-and-after study was conducted. SETTING AND PARTICIPANTS: All the first urinary Enterobacteriaceae isolates obtained from nursing home residents were included. Two time frames were analyzed: 2013-2015 and 2016-2017. METHODS: The antimicrobial stewardship program started in 2015 and was based on (1) 1-day training for use of an "antimicrobial stewardship kit for nursing homes;" and (2) daily support and training of the coordinating physician by an antibiotic mobile team (AMT) in 2 of 3 nursing homes. RESULTS: Overall, 338 urinary isolates were analyzed. Escherichia coli was the most frequent species (212/338, 63%). A significant reduction of resistance to ofloxacin was observed between 2013-2015 and 2016-2017 in general (Delta = -16%, P = .004) and among isolates obtained from patients hospitalized in the county nursing home with AMT support (Delta = -28%, P < .01). A nonstatistically significant reduction in ofloxacin resistance was also observed in the hospital nursing home with AMT support (Delta = -18%, P = .06). CONCLUSIONS AND IMPLICATIONS: Our antimicrobial stewardship program resulted in a decrease in resistance to FLQ among urinary Enterobacteriaceae isolated from nursing home residents. The support of an AMT along with continuous training of the coordinating physician seems to be an important component to ensure efficacy of the intervention. |*Antimicrobial Stewardship[MESH] |Anti-Bacterial Agents/therapeutic use[MESH] |Enterobacteriaceae[MESH] |Fluoroquinolones/therapeutic use[MESH] |Humans[MESH] |Nursing Homes[MESH]Impact of an Antimicrobial Stewardship Program on Resistance to Fluoro(epmc).pdf DeepDyve Pubget Overpricing