Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.gendis.2019.07.010 http://scihub22266oqcxt.onion/10.1016/j.gendis.2019.07.010 32181279!7063432!32181279     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32181279&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Genes+Dis 2020 ; 7 (1): 84-92 Nephropedia Template TP {{tp|p=32181279|t=2020. Recent advances in chronic granulomatous disease |pdf=|usr=}}{{32181279}} gab.com Text Recent advances in chronic granulomatous disease JO: Genes Dis http://www.kidney.de/pget.php?&tw=1&pmid=32181279 #FOAvip Chronic granulomatous disease (CGD) is an inherited defect of phagocyte function due to defective NADPH oxidase. Patients with CGD are not able to effectively clear the infections because of the defect in the phagocyte production of oxygen free radicals and are prone to recurrent bacterial and fungal infections. Inflammatory complications are also noted in CGD such as colitis, non-infective granulomas causing gastrointestinal or urinary tract obstruction, hemophagocytic lymphohistiocytosis, and arthritis. Studies on toll-like receptor pathways and neutrophil extracellular traps in CGD have shed light on the role of NADPH oxidase in the innate immunity and pathogenesis of infections in CGD. Some reports also indicate a reduction of memory B cells and defective production of functional antibodies in CGD. Though the exact mechanisms for non-infective inflammatory complications in CGD are not yet clear, studies on efferocytosis and defective autophagy with inflammasome activation have made a substantial contribution to our understanding of the pathogenesis of inflammation in CGD. We also discuss the clinical and molecular features of p40(phox) defects and a newer genetic defect, EROS. Clinical phenotypes of X-linked carriers of CYBB are also discussed. Twit Text FOAVip Recent advances in chronic granulomatous disease ????Genes Dis http://www.kidney.de/pget.php?&tw=1&pmid=32181279 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32181279 #FOAvip English Wikipedia <ref>{{Cite pmid|32181279}}</ref> Recent advances in chronic granulomatous disease #MMPMID32181279 Anjani G; Vignesh P; Joshi V; Shandilya JK; Bhattarai D; Sharma J; Rawat A Genes Dis 2020[Mar]; 7 (1): 84-92 PMID32181279show ga Chronic granulomatous disease (CGD) is an inherited defect of phagocyte function due to defective NADPH oxidase. Patients with CGD are not able to effectively clear the infections because of the defect in the phagocyte production of oxygen free radicals and are prone to recurrent bacterial and fungal infections. Inflammatory complications are also noted in CGD such as colitis, non-infective granulomas causing gastrointestinal or urinary tract obstruction, hemophagocytic lymphohistiocytosis, and arthritis. Studies on toll-like receptor pathways and neutrophil extracellular traps in CGD have shed light on the role of NADPH oxidase in the innate immunity and pathogenesis of infections in CGD. Some reports also indicate a reduction of memory B cells and defective production of functional antibodies in CGD. Though the exact mechanisms for non-infective inflammatory complications in CGD are not yet clear, studies on efferocytosis and defective autophagy with inflammasome activation have made a substantial contribution to our understanding of the pathogenesis of inflammation in CGD. We also discuss the clinical and molecular features of p40(phox) defects and a newer genetic defect, EROS. Clinical phenotypes of X-linked carriers of CYBB are also discussed. ?Recent advances in chronic granulomatous disease (epmc).pdf DeepDyve Pubget Overpricing