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10.1016/j.jinf.2020.03.001

http://scihub22266oqcxt.onion/10.1016/j.jinf.2020.03.001
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32171867!7102560!32171867
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suck abstract from ncbi


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pmid32171867      J+Infect 2020 ; 80 (5): e14-e17
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  • Clinical characteristics of severe acute respiratory syndrome coronavirus 2 reactivation #MMPMID32171867
  • Ye G; Pan Z; Pan Y; Deng Q; Chen L; Li J; Li Y; Wang X
  • J Infect 2020[May]; 80 (5): e14-e17 PMID32171867show ga
  • OBJECTIVES: Previous studies on the pneumonia outbreak caused by the 2019 novel coronavirus disease (COVID-19) were based on information from the general population. However, limited data was available for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reactivation. This study aimed to evaluate the clinical characteristics of the SARS-CoV-2 reactivation. METHODS: Clinical records, laboratory results, and chest CT scans were retrospectively reviewed for 55 patients with laboratory-confirmed COVID-19 pneumonia (i.e., with throat swab samples that were positive for SARS-CoV-2) who were admitted to Zhongnan Hospital of Wuhan University, Wuhan, China, from Jan. 8 to Feb. 10, 2020. RESULTS: All 55 patients had a history of epidemiological exposure to COVID-19, and 5 (9%) patients who discharged from hospital presented with SARS-CoV-2 reactivation. Among the 5 reactivated patients, other symptoms were also observed, including fever, cough, sore throat, and fatigue. One of the 5 patients had progressive lymphopenia (from 1.3 to 0.56?x?10(9) cells per L) and progressive neutrophilia (from 4.5 to 18.28?x?10(9) cells per L). All 5 reactivated patients presented normal aminotransferase levels. Throat swab samples from the 5 reactivated patients were tested for SARS-CoV-2, indicating all positive for the virus. CONCLUSIONS: Findings from this small group of cases suggested that there was currently evidence for reactivation of SARS-CoV-2 and there might be no specific clinical characteristics to distinguish them.
  • |*Tomography, X-Ray Computed[MESH]
  • |Adult[MESH]
  • |Betacoronavirus/isolation & purification[MESH]
  • |COVID-19[MESH]
  • |China[MESH]
  • |Coronavirus Infections/blood/*diagnostic imaging/*pathology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Pharynx/virology[MESH]
  • |Pneumonia, Viral/blood/*diagnostic imaging/*pathology[MESH]
  • |Recurrence[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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