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10.1016/j.ijantimicag.2020.105938 http://scihub22266oqcxt.onion/10.1016/j.ijantimicag.2020.105938 32171740!7118659!32171740     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Antimicrob+Agents 2020 ; 55 (5): 105938 Nephropedia Template TP {{tp|p=32171740|t=2020. New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?|pdf=|usr=}}{{32171740}} gab.com Text New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19 JO: Int J Antimicrob Agents http://www.kidney.de/pget.php?&tw=1&pmid=32171740 #FOAvip Recently, a novel coronavirus (2019-nCoV), officially known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China. Despite drastic containment measures, the spread of this virus is ongoing. SARS-CoV-2 is the aetiological agent of coronavirus disease 2019 (COVID-19) characterised by pulmonary infection in humans. The efforts of international health authorities have since focused on rapid diagnosis and isolation of patients as well as the search for therapies able to counter the most severe effects of the disease. In the absence of a known efficient therapy and because of the situation of a public-health emergency, it made sense to investigate the possible effect of chloroquine/hydroxychloroquine against SARS-CoV-2 since this molecule was previously described as a potent inhibitor of most coronaviruses, including SARS-CoV-1. Preliminary trials of chloroquine repurposing in the treatment of COVID-19 in China have been encouraging, leading to several new trials. Here we discuss the possible mechanisms of chloroquine interference with the SARS-CoV-2 replication cycle. Twit Text FOAVip New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19 ????Int J Antimicrob Agents http://www.kidney.de/pget.php?&tw=1&pmid=32171740 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32171740 #FOAvip English Wikipedia <ref>{{Cite pmid|32171740}}</ref> New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19? #MMPMID32171740 Devaux CA; Rolain JM; Colson P; Raoult D Int J Antimicrob Agents 2020[May]; 55 (5): 105938 PMID32171740show ga Recently, a novel coronavirus (2019-nCoV), officially known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China. Despite drastic containment measures, the spread of this virus is ongoing. SARS-CoV-2 is the aetiological agent of coronavirus disease 2019 (COVID-19) characterised by pulmonary infection in humans. The efforts of international health authorities have since focused on rapid diagnosis and isolation of patients as well as the search for therapies able to counter the most severe effects of the disease. In the absence of a known efficient therapy and because of the situation of a public-health emergency, it made sense to investigate the possible effect of chloroquine/hydroxychloroquine against SARS-CoV-2 since this molecule was previously described as a potent inhibitor of most coronaviruses, including SARS-CoV-1. Preliminary trials of chloroquine repurposing in the treatment of COVID-19 in China have been encouraging, leading to several new trials. Here we discuss the possible mechanisms of chloroquine interference with the SARS-CoV-2 replication cycle. |Antiviral Agents/pharmacology/*therapeutic use[MESH] |Betacoronavirus/*drug effects[MESH] |COVID-19[MESH] |Chloroquine/pharmacology/*therapeutic use[MESH] |Coronavirus Infections/*drug therapy[MESH] |Drug Evaluation, Preclinical[MESH] |Humans[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy[MESH]New insights on the antiviral effects of chloroquine against coronavir(epmc).pdf DeepDyve Pubget Overpricing