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10.23736/S1121-421X.20.02697-5

http://scihub22266oqcxt.onion/10.23736/S1121-421X.20.02697-5
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32162896!ä!32162896

suck abstract from ncbi


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pmid32162896      Minerva+Gastroenterol+Dietol 2020 ; 66 (2): 172-176
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  • Possible therapeutic role of a highly standardized mixture of active compounds derived from cultured Lentinula edodes mycelia (AHCC) in patients infected with 2019 novel coronavirus #MMPMID32162896
  • Di Pierro F; Bertuccioli A; Cavecchia I
  • Minerva Gastroenterol Dietol 2020[Jun]; 66 (2): 172-176 PMID32162896show ga
  • The outbreak of SARS-CoV-2 disease (COVID-19) is currently, March 2020, affecting more than 100,000 people worldwide and, according to the WHO (World Health Organization), a pandemic is shortly expected. The virus infects the lower respiratory tract and causes severe pneumonia and mortality in approximately 10% and 3-5%, respectively, of cases, mainly among the elderly and/or people affected by other diseases. AHCC is an alpha-glucan-based standardized mushroom extract that has been extensively investigated as an immunostimulant both in animals and/or in humans affected by West Nile virus, influenza virus, avian influenza virus, hepatitis C virus, papillomavirus, herpes virus, hepatitis B virus and HIV by promoting a regulated and protective immune response. Although the efficacy of AHCC has not yet been specifically evaluated with respect to SARS-CoV-2 disease, its action in promoting a protective response to a wide range of viral infections, and the current absence of effective vaccines, could support its use in the prevention of diseases provoked by human pathogenic coronavirus, including COVID-19.
  • |*Betacoronavirus/immunology[MESH]
  • |*Shiitake Mushrooms[MESH]
  • |Adjuvants, Immunologic/*pharmacology[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*drug therapy[MESH]
  • |Humans[MESH]
  • |Mycelium[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy[MESH]
  • |Polysaccharides/*pharmacology[MESH]


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