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10.1016/j.dld.2020.02.003

http://scihub22266oqcxt.onion/10.1016/j.dld.2020.02.003
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suck abstract from ncbi


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pmid32122771      Dig+Liver+Dis 2020 ; 52 (5): 547-554
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  • Epidemiology, clinical features and diagnostic work-up of cystic neoplasms of the pancreas: Interim analysis of the prospective PANCY survey #MMPMID32122771
  • Pezzilli R; Buscarini E; Pollini T; Bonamini D; Marchegiani G; Crippa S; Belfiori G; Sperti C; Moletta L; Pozza G; De Nucci G; Manes G; Mandelli ED; Casadei R; Ricci C; Alicante S; Vattiato C; Carrara S; Di Leo M; Fabbri C; Giovanelli S; Barresi L; Tacelli M; Mirante VG; Conigliaro R; Antonini F; Macarri G; Frulloni L; De Marchi G; Sassatelli R; Cecinato P; Del Vecchio Blanco G; Galli A; Pezzullo A; Fantin A; Graffeo M; Frego M; Stillittano D; Monica F; Germana B; Capurso G; Quartini M; Veneroni L; Cannizzaro R; Falconi M
  • Dig Liver Dis 2020[May]; 52 (5): 547-554 PMID32122771show ga
  • INTRODUCTION: A prospective survey to evaluate the diagnostic workup of cystic pancreatic neoplasms (CPNs) according to the Italian guidelines. METHODS: An online data sheet was built. RESULTS: Fifteen of the 1385 patients (1.1%) had non cystic neoplastic lesions. Forty percent (518/1295) had at least one 1st degree relative affected by a solid tumor of the digestive and extra-digestive organs. Symptoms/signs associated with the cystic lesion were present in 24.5% of the patients. The cysts were localized in the head of the pancreas in 38.5% of patients. Of the 2370 examinations (1.7 examinations per patient) which were carried out for the diagnosis, magnetic resonance imaging was performed as a single test in 48.4% of patients and in combination with endoscopic ultrasound in 27% of the cases. Of the 1370 patients having CPNs, 89.9% had an intraductal papillary mucinous neoplasm (IPMN) (70.1% a branch duct IPMN, 6.2% a mixed type IPMN and 4.6% a main duct IPMN), 12.7% had a serous cystadenoma, 2.8% a mucinous cystadenoma, 1.5% a non-functioning cystic neuroendocrine neoplasm, 0.7% a solid-pseudopapillary cystic neoplasm, 0.3% a cystic adenocarcinoma, and 1.2% an undetermined cystic neoplasm. Seventy-eight (5.7%) patients were operated upon after the initial work-up. CONCLUSIONS: This prospective study offers a reliable real-life picture of the diagnostic work-up CPN.
  • |Adenocarcinoma/epidemiology[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Cystadenoma, Mucinous/*epidemiology[MESH]
  • |Cystadenoma, Serous/*epidemiology[MESH]
  • |Endosonography[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Italy/epidemiology[MESH]
  • |Magnetic Resonance Imaging[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Neuroendocrine Tumors/epidemiology[MESH]
  • |Pancreas/*diagnostic imaging/*pathology[MESH]
  • |Pancreatic Neoplasms/*epidemiology[MESH]
  • |Practice Guidelines as Topic[MESH]
  • |Prospective Studies[MESH]
  • |Surveys and Questionnaires[MESH]


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