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10.3346/jkms.2020.35.e84

http://scihub22266oqcxt.onion/10.3346/jkms.2020.35.e84
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32080990!7036342!32080990
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suck abstract from ncbi


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pmid32080990      J+Korean+Med+Sci 2020 ; 35 (7): e84
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  • Virus Isolation from the First Patient with SARS-CoV-2 in Korea #MMPMID32080990
  • Park WB; Kwon NJ; Choi SJ; Kang CK; Choe PG; Kim JY; Yun J; Lee GW; Seong MW; Kim NJ; Seo JS; Oh MD
  • J Korean Med Sci 2020[Feb]; 35 (7): e84 PMID32080990show ga
  • Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan since December 2019 in China and SARS-CoV-2 infections have been reported with epidemiological linkage to China in 25 countries until now. We isolated SARS-CoV-2 from the oropharyngeal sample obtained from the patient with the first laboratory-confirmed SARS-CoV-2 infection in Korea. Cytopathic effects of SARS-CoV-2 in the Vero cell cultures were confluent 3 days after the first blind passage of the sample. Coronavirus was confirmed with spherical particle having a fringe reminiscent of crown on transmission electron microscopy. Phylogenetic analyses of whole genome sequences showed that it clustered with other SARS-CoV-2 reported from Wuhan.
  • |*Betacoronavirus/genetics/isolation & purification[MESH]
  • |*Coronavirus Infections/diagnosis[MESH]
  • |*Pneumonia, Viral/diagnosis[MESH]
  • |*Whole Genome Sequencing[MESH]
  • |Adult[MESH]
  • |COVID-19[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Microscopy, Electron, Transmission[MESH]
  • |Oropharynx/*virology[MESH]
  • |Phylogeny[MESH]
  • |Republic of Korea[MESH]


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