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10.1007/s10554-020-01775-y

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32056087!7174273!32056087
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suck abstract from ncbi


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pmid32056087      Int+J+Cardiovasc+Imaging 2020 ; 36 (5): 899-911
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  • A multi-vendor, multi-center study on reproducibility and comparability of fast strain-encoded cardiovascular magnetic resonance imaging #MMPMID32056087
  • Erley J; Zieschang V; Lapinskas T; Demir A; Wiesemann S; Haass M; Osman NF; Simonetti OP; Liu Y; Patel AR; Mor-Avi V; Unal O; Johnson KM; Pieske B; Hansmann J; Schulz-Menger J; Kelle S
  • Int J Cardiovasc Imaging 2020[May]; 36 (5): 899-911 PMID32056087show ga
  • Myocardial strain is a convenient parameter to quantify left ventricular (LV) function. Fast strain-encoding (fSENC) enables the acquisition of cardiovascular magnetic resonance images for strain-measurement within a few heartbeats during free-breathing. It is necessary to analyze inter-vendor agreement of techniques to determine strain, such as fSENC, in order to compare existing studies and plan multi-center studies. Therefore, the aim of this study was to investigate inter-vendor agreement and test-retest reproducibility of fSENC for three major MRI-vendors. fSENC-images were acquired three times in the same group of 15 healthy volunteers using 3 Tesla scanners from three different vendors: at the German Heart Institute Berlin, the Charite University Medicine Berlin-Campus Buch and the Theresien-Hospital Mannheim. Volunteers were scanned using the same imaging protocol composed of two fSENC-acquisitions, a 15-min break and another two fSENC-acquisitions. LV global longitudinal and circumferential strain (GLS, GCS) were analyzed by a trained observer (Myostrain 5.0, Myocardial Solutions) and for nine volunteers repeatedly by another observer. Inter-vendor agreement was determined using Bland-Altman analysis. Test-retest reproducibility and intra- and inter-observer reproducibility were analyzed using intraclass correlation coefficient (ICC) and coefficients of variation (CoV). Inter-vendor agreement between all three sites was good for GLS and GCS, with biases of 0.01-1.88%. Test-retest reproducibility of scans before and after the break was high, shown by ICC- and CoV values of 0.63-0.97 and 3-9% for GLS and 0.69-0.82 and 4-7% for GCS, respectively. Intra- and inter-observer reproducibility were excellent for both parameters (ICC of 0.77-0.99, CoV of 2-5%). This trial demonstrates good inter-vendor agreement and test-retest reproducibility of GLS and GCS measurements, acquired at three different scanners from three different vendors using fSENC. The results indicate that it is necessary to account for a possible bias (< 2%) when comparing strain measurements of different scanners. Technical differences between scanners, which impact inter-vendor agreement, should be further analyzed and minimized.DRKS Registration Number: 00013253.Universal Trial Number (UTN): U1111-1207-5874.
  • |*Magnetic Resonance Imaging/instrumentation[MESH]
  • |*Myocardial Contraction[MESH]
  • |*Ventricular Function, Left[MESH]
  • |Adult[MESH]
  • |Equipment Design[MESH]
  • |Female[MESH]
  • |Germany[MESH]
  • |Healthy Volunteers[MESH]
  • |Heart Ventricles/*diagnostic imaging[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Observer Variation[MESH]
  • |Reproducibility of Results[MESH]


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