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10.1016/j.drudis.2020.01.015 http://scihub22266oqcxt.onion/10.1016/j.drudis.2020.01.015 32006468!7102522!32006468     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Drug+Discov+Today 2020 ; 25 (4): 668-688 Nephropedia Template TP {{tp|p=32006468|t=2020. Recent discovery and development of inhibitors targeting coronaviruses |pdf=|usr=}}{{32006468}} gab.com Text Recent discovery and development of inhibitors targeting coronaviruses JO: Drug Discov Today http://www.kidney.de/pget.php?&tw=1&pmid=32006468 #FOAvip Human coronaviruses (CoVs) are enveloped viruses with a positive-sense single-stranded RNA genome. Currently, six human CoVs have been reported including human coronavirus 229E (HCoV-229E), OC43 (HCoV-OC43), NL63 (HCoV-NL63), HKU1 (HCoV-HKU1), severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV), and MiddleEast respiratory syndrome (MERS) coronavirus (MERS-CoV). They cause moderate to severe respiratory and intestinal infections in humans. In this review, we focus on recent advances in the research and development of small-molecule anti-human coronavirus therapies targeting different stages of the CoV life cycle. Twit Text FOAVip Recent discovery and development of inhibitors targeting coronaviruses ????Drug Discov Today http://www.kidney.de/pget.php?&tw=1&pmid=32006468 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32006468 #FOAvip English Wikipedia <ref>{{Cite pmid|32006468}}</ref> Recent discovery and development of inhibitors targeting coronaviruses #MMPMID32006468 Pillaiyar T; Meenakshisundaram S; Manickam M Drug Discov Today 2020[Apr]; 25 (4): 668-688 PMID32006468show ga Human coronaviruses (CoVs) are enveloped viruses with a positive-sense single-stranded RNA genome. Currently, six human CoVs have been reported including human coronavirus 229E (HCoV-229E), OC43 (HCoV-OC43), NL63 (HCoV-NL63), HKU1 (HCoV-HKU1), severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV), and MiddleEast respiratory syndrome (MERS) coronavirus (MERS-CoV). They cause moderate to severe respiratory and intestinal infections in humans. In this review, we focus on recent advances in the research and development of small-molecule anti-human coronavirus therapies targeting different stages of the CoV life cycle. |*Drug Design[MESH] |*Drug Development[MESH] |*Molecular Targeted Therapy[MESH] |Animals[MESH] |Antiviral Agents/adverse effects/chemistry/*therapeutic use[MESH] |Coronaviridae Infections/diagnosis/*drug therapy/virology[MESH] |Coronavirus/*drug effects/growth & development/pathogenicity[MESH] |Humans[MESH] |Molecular Structure[MESH]Recent discovery and development of inhibitors targeting coronaviruses(epmc).pdf DeepDyve Pubget Overpricing