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10.1002/jmv.25688 http://scihub22266oqcxt.onion/10.1002/jmv.25688 31994738!7166400!31994738     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Med+Virol 2020 ; 92 (4): 455-459 Nephropedia Template TP {{tp|p=31994738|t=2020. The 2019-new coronavirus epidemic: Evidence for virus evolution |pdf=|usr=}}{{31994738}} gab.com Text The 2019-new coronavirus epidemic: Evidence for virus evolution JO: J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=31994738 #FOAvip There is a worldwide concern about the new coronavirus 2019-nCoV as a global public health threat. In this article, we provide a preliminary evolutionary and molecular epidemiological analysis of this new virus. A phylogenetic tree has been built using the 15 available whole genome sequences of 2019-nCoV, 12 whole genome sequences of 2019-nCoV, and 12 highly similar whole genome sequences available in gene bank (five from the severe acute respiratory syndrome, two from Middle East respiratory syndrome, and five from bat SARS-like coronavirus). Fast unconstrained Bayesian approximation analysis shows that the nucleocapsid and the spike glycoprotein have some sites under positive pressure, whereas homology modeling revealed some molecular and structural differences between the viruses. The phylogenetic tree showed that 2019-nCoV significantly clustered with bat SARS-like coronavirus sequence isolated in 2015, whereas structural analysis revealed mutation in Spike Glycoprotein and nucleocapsid protein. From these results, the new 2019-nCoV is distinct from SARS virus, probably trasmitted from bats after mutation conferring ability to infect humans. Twit Text FOAVip The 2019-new coronavirus epidemic: Evidence for virus evolution ????J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=31994738 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31994738 #FOAvip English Wikipedia <ref>{{Cite pmid|31994738}}</ref> The 2019-new coronavirus epidemic: Evidence for virus evolution #MMPMID31994738 Benvenuto D; Giovanetti M; Ciccozzi A; Spoto S; Angeletti S; Ciccozzi M J Med Virol 2020[Apr]; 92 (4): 455-459 PMID31994738show ga There is a worldwide concern about the new coronavirus 2019-nCoV as a global public health threat. In this article, we provide a preliminary evolutionary and molecular epidemiological analysis of this new virus. A phylogenetic tree has been built using the 15 available whole genome sequences of 2019-nCoV, 12 whole genome sequences of 2019-nCoV, and 12 highly similar whole genome sequences available in gene bank (five from the severe acute respiratory syndrome, two from Middle East respiratory syndrome, and five from bat SARS-like coronavirus). Fast unconstrained Bayesian approximation analysis shows that the nucleocapsid and the spike glycoprotein have some sites under positive pressure, whereas homology modeling revealed some molecular and structural differences between the viruses. The phylogenetic tree showed that 2019-nCoV significantly clustered with bat SARS-like coronavirus sequence isolated in 2015, whereas structural analysis revealed mutation in Spike Glycoprotein and nucleocapsid protein. From these results, the new 2019-nCoV is distinct from SARS virus, probably trasmitted from bats after mutation conferring ability to infect humans. |*Chiroptera[MESH] |*Coronavirus[MESH] |*Coronavirus Infections[MESH] |*Severe acute respiratory syndrome-related coronavirus[MESH] |Animals[MESH] |Bayes Theorem[MESH] |Betacoronavirus[MESH] |Evolution, Molecular[MESH] |Humans[MESH] |Phylogeny[MESH] |SARS-CoV-2[MESH]The 2019-new coronavirus epidemic: Evidence for virus evolution (epmc).pdf DeepDyve Pubget Overpricing