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10.1007/s00705-019-04488-3

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31982944!7087231!31982944
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suck abstract from ncbi


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pmid31982944      Arch+Virol 2020 ; 165 (3): 703-707
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  • A recombinant infectious bronchitis virus from a chicken with a spike gene closely related to that of a turkey coronavirus #MMPMID31982944
  • Wang Y; Cui X; Chen X; Yang S; Ling Y; Song Q; Zhu S; Sun L; Li C; Li Y; Deng X; Delwart E; Zhang W
  • Arch Virol 2020[Mar]; 165 (3): 703-707 PMID31982944show ga
  • Using viral metagenomics, the complete genome sequence of an infectious bronchitis virus (IBV) strain (named ahysx-1) from a fecal sample from a healthy chicken in Anhui province, China, was determined. The genome sequence of ahysx-1 was found to be very similar to that of IBV strain ck/CH/LLN/131040 (KX252787), except for the spike gene region, which is similar to that of a turkey coronavirus strain (EU022526), suggesting that ahysx-1 is a recombinant. Recombination analysis and phylogenetic analysis based on the genomic sequences of ahysx-1 and other related strains confirmed that ahysx-1 appears to be a recombinant resulting from a recombination event that occurred between a chicken coronavirus and a turkey coronavirus. Further studies need to be performed to determine whether this recombinant IBV strain is pathogenic and whether it is transmitted between chickens and turkeys.
  • |*Recombination, Genetic[MESH]
  • |Animals[MESH]
  • |Chickens/*virology[MESH]
  • |Coronavirus/*genetics[MESH]
  • |Genome, Viral[MESH]
  • |Infectious bronchitis virus/*genetics[MESH]
  • |Metagenomics[MESH]
  • |Phylogeny[MESH]
  • |Spike Glycoprotein, Coronavirus/*genetics[MESH]


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