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10.1016/j.micpath.2020.103998 http://scihub22266oqcxt.onion/10.1016/j.micpath.2020.103998 31982568!7125550!31982568     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=31982568&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Microb+Pathog 2020 ; 141 (ä): 103998 Nephropedia Template TP {{tp|p=31982568|t=2020. Gga-miR-30d regulates infectious bronchitis virus infection by targeting USP47 in HD11 cells |pdf=|usr=}}{{31982568}} gab.com Text Gga-miR-30d regulates infectious bronchitis virus infection by targeting USP47 in HD11 cells JO: Microb Pathog http://www.kidney.de/pget.php?&tw=1&pmid=31982568 #FOAvip Avian infectious bronchitis virus (IBV) is a coronavirus which infects chickens and causes severe economic losses to the poultry industry worldwide. MicroRNAs (miRNAs) are important intracellular regulators and play a pivotal role in viral infections. In previous studies, we have revealed that IBV infection caused a significant down-regulation of gga-miR-30d expression in chicken kidneys. In present study, we investigated the role of gga-miR-30d in the process of IBV infection of HD11 cell line in vitro. By transfecting the mimics and inhibitor of gga-miR-30d, it was found that overexpressed gga-miR-30d inhibited IBV replication. Contrarily, low-expressed gga-miR-30d promoted IBV replication. In addition, dual-luciferase reporter assays revealed that ubiquitin-specific protease 47 (USP47), a deubiquitinase-encoding gene, was a target for gga-miR-30d. This is the first study demonstrating that miRNAs regulate IBV replication by regulating the deubiquitinating enzyme (DUBs). Twit Text FOAVip Gga-miR-30d regulates infectious bronchitis virus infection by targeting USP47 in HD11 cells ????Microb Pathog http://www.kidney.de/pget.php?&tw=1&pmid=31982568 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31982568 #FOAvip English Wikipedia <ref>{{Cite pmid|31982568}}</ref> Gga-miR-30d regulates infectious bronchitis virus infection by targeting USP47 in HD11 cells #MMPMID31982568 Li H; Li J; Zhai Y; Zhang L; Cui P; Feng L; Yan W; Fu X; Tian Y; Wang H; Yang X Microb Pathog 2020[Apr]; 141 (ä): 103998 PMID31982568show ga Avian infectious bronchitis virus (IBV) is a coronavirus which infects chickens and causes severe economic losses to the poultry industry worldwide. MicroRNAs (miRNAs) are important intracellular regulators and play a pivotal role in viral infections. In previous studies, we have revealed that IBV infection caused a significant down-regulation of gga-miR-30d expression in chicken kidneys. In present study, we investigated the role of gga-miR-30d in the process of IBV infection of HD11 cell line in vitro. By transfecting the mimics and inhibitor of gga-miR-30d, it was found that overexpressed gga-miR-30d inhibited IBV replication. Contrarily, low-expressed gga-miR-30d promoted IBV replication. In addition, dual-luciferase reporter assays revealed that ubiquitin-specific protease 47 (USP47), a deubiquitinase-encoding gene, was a target for gga-miR-30d. This is the first study demonstrating that miRNAs regulate IBV replication by regulating the deubiquitinating enzyme (DUBs). |*Virus Replication[MESH] |Animals[MESH] |Cell Line[MESH] |Chickens[MESH] |Coronavirus Infections/genetics/metabolism/*veterinary/virology[MESH] |Host-Parasite Interactions[MESH] |Infectious bronchitis virus/genetics/*physiology[MESH] |MicroRNAs/genetics/*metabolism[MESH] |Poultry Diseases/*enzymology/genetics/metabolism/virology[MESH]Gga-miR-30d regulates infectious bronchitis virus infection by targeti(epmc).pdf DeepDyve Pubget Overpricing